摘要
目的：通过调查山西省部分县（市）出生缺陷现状,分析探讨出生缺陷发生相关因素。方法：以2006年1月~2008年12月山西省6县（市）出生儿为调查对象,调查出生缺陷发生率,居住地和家庭收入情况,母亲年龄、文化程度、家族史、孕产史、既往史、个人史及是否接受婚育指导、是否增补叶酸,孕期患病及服药情况、接触有害物质情况、出生儿情况等。结果：近3年现存出生缺陷率为134.27万/,排在前4位的依次为先天性心脏病、神经管畸形、唇腭裂、多指（趾）与并指（趾）。出生缺陷的发生率和居住地、家庭年人均收入、母亲年龄和文化程度密切相关;近亲结婚、曾生育缺陷儿、亲属曾生育缺陷儿家庭的出生缺陷发生率均处在较高水平。母亲孕期罹患发热、上呼吸道感染、先兆流产、生殖道感染、妊娠剧吐,以及孕期使用感冒药、止吐药均可使出生缺陷发生率处在较高水平。结论：出生缺陷的发生与多种因素相关,应进行针对性的预防和干预。
Objective： To explore related factors of birth defects through status survey of birth defects in six counties of Shanxi Province.Methods： The infants born in six counties of Shanxi Province between Jan 2006 and Dec 2008 were recruited.The incidence of birth defects,residence of their parents,family income,and maternal age,educational level,family history,previous obstetric history,diet,folic acid supplement as well as illness,medication,circumstance and so on were considered.Results： The prevalence rate of birth defects was 134.27 per 10 000 living children.The top four birth defects were congenital heart disease,neural tube malformation,cleft palate and hyperdactylia.The incidence of birth defects was related to the residence of the parents,family income,maternal age and the educational level.The consanguineous marriage as well as fever,threatened abortion,reproductive tract infection,hyperemesis gravidarum and some medication during pregnancy were risk factors of birth defects.Conclusion： Birth defects are relevant to multiple factors,on which the prevention and intervention should be conducted.
出处
《中国计划生育学杂志》
北大核心
2011年第6期342-346,共5页
Chinese Journal of Family Planning
关键词
出生缺陷
发生率
影响因素
调查
Birth defect
Prevalence
Influencing factor
Survey
