摘要
目的及时了解我院临床分离的肺炎克雷伯菌的耐药性状况,以指导临床合理使用抗菌药物。方法对2010年7月1日～2010年10月1日临床分离的139株肺炎克雷伯菌采用纸微量稀释法测定菌株对庆大霉素等18种抗菌药物的敏感性。结果 139株肺炎克雷伯菌对氨苄西林、头孢唑啉、头孢噻肟、头孢曲松、复方新诺明、庆大霉素、头孢西丁、氨曲南、环丙沙星、阿莫西林/棒酸、妥布霉素、头孢他啶、头孢吡肟、左氧氟沙星、头孢哌酮/舒巴坦、阿米卡星、哌拉西林/他唑巴坦、亚胺培南的耐药率分别为100%、68%、58%、58%、57%、43%、36%、36%、32%、32%、31%、31%、28%、28%、21%、16%、9%、4%。结论我院临床分离的肺炎克雷伯菌对头孢哌酮/舒巴坦和哌拉西林/他唑巴坦的耐药率较低,临床因肺炎克雷伯菌引起的感染可经验使用头孢哌酮/舒巴坦或哌拉西林/他唑巴坦。
Objective：To comprehend promptly the drug resistance condition of Klebsiella pneumoniae separated from clinical divisions of Taian city Central Hospital in order to guide the rational use of antibacterials.Methods： From July 1,2010 to October 1,2010,the paper Microdilution method was used to test the sensibility of 139 Klebsiella pneumoniae strains separated from clinical division to 18 kinds of antibacterials.Results： The drug resistance incidences of 139 Klebsiella pneumoniae strains to Ampicil were 100%,and 68% to Cefazolin,58% to Cefotaxim,58% to Ceftriaxone,57% to SMZ-TMP,43% to Cidomycin,36% to Cefoxitin,36% to Aztreonam,32% to Ciprofloxacin,32% to Amoxicillin/Clavulanic Acid,31% to Tenebrimycin,31% to Ceftazidime,28% to Cefepime,28% to Levofloxacin,21% to Cefoperazone/Sulbactam,16% to Amikacin,9% to Piperacillin/ Tazobactam,4% to Imipenem,respectively.Conclusion： The drug resistance incidences of Klebsiella pneumoniae separated from clinical divisions to Cefoperazone/Sulbactam or Piperacillin/ Tazobactam is lower comparatively,and Cefoperazone/Sulbactam or Piperacillin/ Tazobactam can be used empirically for the infection originated from Klebsiella pneumoniae.
出处
《泰山医学院学报》
CAS
2011年第3期195-196,共2页
Journal of Taishan Medical College
关键词
肺炎克雷伯菌
耐药性
敏感性
Klebsiella pneumoniae
drug resistance
drug sentibility
