摘要
目的:研究3.0T场强下颈椎间盘突出压迫颈髓损伤早期的扩散张量成像(DTI)表现及其临床应用价值。方法:使用单次激发自旋回波平面回波(SE-EPI)序列,对30例健康志愿者及30例颈椎间盘突出患者行常规磁共振(MRI)和横轴面DTI扫描,在C3～7水平分别测量各间盘水平表观扩散系数(ADC)值和部分各向异性(FA)值。结果:正常脊髓C3～7水平间ADC及FA值无差别(F=0.66,P=0.6195;F=1.99,P=0.1027),病例组受压部位和对照组的ADC值、FA值有统计学意义(t′=2.0930,P<0.05;t=11.2136,P<0.001)。在发现脊髓压迫早期损伤时,ADC值的敏感度73.33%,特异性100%,FA值的敏感度和特异度分别为83.33%和100%。结论:DTI对判断脊髓慢性压迫早期损伤有一定价值,FA值敏感性较高。
Objective：To study the clinical feature and application value of diffusion tensor imaging at 3.0T in early cervical spinal cord compression.Methods：Routine MRI and axial DTI were performed in 30 cases of healthy subjects and 30 cases of cervical spinal cord compression by using SE-EPI sequence.The value of apparent diffusion Coefficient（ADC） and fractional anisotropy（FA） were measured in the cervical cords.The regions of interest were placed at the level of C2-C7.Results：There were no statistically significant differences between ADC and FA in the level of C3-C7（F=0.66,P=0.6195;F=1.99,P=0.1027）.Among 30 cases of spinal cord compression,there were statistically significant difference between the case group and control group （t′=2.0930,P0.05;t=11.2136,P0.001）.Sensitivity of FA and ADC were 83.33% and 73.33% respectively.Specificity of FA and ADC were 100%.Conclusion：DTI may be helpful in assessing the chronic early cervical spinal cord compressions.FA value has high sensitivity for detection of cervical spinal cord compression.
出处
《内蒙古医学杂志》
2011年第4期406-409,共4页
Inner Mongolia Medical Journal
关键词
脊髓压迫
颈椎间盘突出
磁共振成像
扩散张量成像
Spinal cord compression
Cervical prolapsed vertebral disc
Magnetic resonance imaging
Diffusion tensor imaging
