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蛋白质组学技术在神经毒理学研究中的应用 被引量:2

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摘要 蛋白质组是指一个基因组、一个细胞、组织或一种生物体所表达的全部蛋白质。蛋白质组学是指用来研究蛋白质组的学科,主要包括蛋白质分离、鉴定与生物信息学分析等技术。
出处 《毒理学杂志》 CAS CSCD 北大核心 2011年第2期141-145,共5页 Journal of Toxicology
基金 北京市留学人员科技活动择优资助项目(2007-62) 北京市"十百千"卫生人才培养专项经费资助(2007-29"百"层次 2009-1"十"层次) 北京市科委市属公益院所改革与发展项目
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  • 1LoPachin RM, Jones RC, Patterson TA, et al. Application of Proteomics to the Study of Molecular Mechanisms in Neurotoxicology [ J ]. Neurotoxicology,2003, 24 (6) : 761 - 775.
  • 2李春阳,李林.蛋白质组学技术在神经系统疾病研究中的作用[J].生理科学进展,2005,36(3):286-288. 被引量:4
  • 3何胜祥,陈平,郭占云,邵晓霞.蛋白质组学在神经退行性疾病中的研究进展[J].细胞生物学杂志,2007,29(2):173-178. 被引量:1
  • 4李习艺,庄志雄.蛋白质组学技术及其在毒理学应用的研究进展[J].毒理学杂志,2005,19(4):316-319. 被引量:4
  • 5Harvey DJ. Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update for the period 2005-2006 [ J ]. Mass Spectrom Rev,2011, 30( 1 ) : 1-100.
  • 6Chalkley RJ, Burlingame AL. Identification of GlcNAcylation sites of peptides and alpha-crystallin using Q-TOF mass spectrometry [J] J Am Soc Mass Spectrom, 2001,12 (10) :1106-1113.
  • 7Ma Y, Lu Y, Zheng H, et al. Characterization of phosphopeptides from protein digests using matrix assisted laser desorption/ionization time-of-flight mass spectrometry and nanoelectrospray quadrupole time-of-flight mass spectrometry[J]. Rapid Commun Mass Spectrom, 2001, 15(18) :1693-1700.
  • 8Raman K. Construction and analysis of protein-protein interaction networks [ J ]. Autom Exp Published online, 2010, 2(1) :2.
  • 9LoPachin RM, Balaban CD, Ross JF. Acrylamide axonopathy revisited [ J]. Toxicol Appl Pharmacol, 2003, 188 (3) :135-153.
  • 10Barber DS, Stevens S, LoPachin RM. Proteomic analysis of rat striatal synaptosomes during aerylamide intoxication at a low dose rate [ J ]. Toxicol Sci, 2007,100 ( 1 ) : 156-167.

二级参考文献89

  • 1Fearnley J M,Lees A J.Ageing and Parkinson's disease:substantia nigra regional selectivity[J].Brain,1991,114:2283-2301.
  • 2Michell A W,Lewis S J,Foltynie T,et al.Biomarkers and Parkinson's diseas[J].Brain,2004,127:1693-1705.
  • 3Gerlach M,Hendrich A,Hueber R,et al.Early Detection of Parkinson's Disease:unmet needs[J].Neurodegener Dis,2008,5:137-139.
  • 4Riederer P,Wuketich S.Time course of nigrostriatal degeneration in Parkinson's disease.A detailed study of influential factors in human brain amine analysis[J].J Neural Transm,1976,38:277-301.
  • 5Dotzlaw H,Schulz M,Eggert M,et al.A pattern of protein expression in peripheral blood mononuclear cells distinguishes rheumatoid arthritis patients from healthy individuals[J].Biochim Biophys Acta,2004,1696:121-129.
  • 6Kang X,Xu Y,Wu X,et al.Proteomic fingerprints for potential application to early diagnosis of severe acute respiratory syndrome[J].Clin Chem,2005,51:56--64.
  • 7Stebbins G T,Goetz C G.Factor structure of the Unified Parkinson's Disease Reting Scale:Motor Examination section[J].Mov Disord,1998,13:633-636.
  • 8Mian S,Ugurel S,Parkinson E,et al.Serum proteomic fingerprinting discriminates between clinical stages and predicts disease progression in melanoma patients[J].J Clin Oncol,2005,23:5088-5093.
  • 9Varghese S A,Powell T B,Budisavljevic M N,et al.Urine hiomarkers predict the cause of glomerular disease[J].J Am Soc Nephrol,2007,18:913-922.
  • 10Gasser T.Genetics of Parkinson's disease[J].Curr Opin Neurol,2005,18:363-369.

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