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IL-6表达与腺样体肥大伴分泌性中耳炎发病的关系 被引量：6

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摘要 目的检测白细胞介素-6(IL-6)在单纯腺样体肥大及腺样体肥大伴分泌性中耳炎(otitis mediawith effusion,OME)患儿的腺样体组织及血清中的表达,探讨IL-6与OME发病的关系。方法单纯腺样体肥大组患儿20例(男12例,女8例),腺样体肥大伴OME组患儿20例(男11例,女9例),分别检测两组患儿腺样体组织及血清中IL-6的表达并进行比较。结果腺样体肥大伴分泌性中耳炎组腺样体组织中IL-6的表达明显高于单纯腺样体肥大组(P<0.05),两组患儿血清中IL-6的表达差异无统计学意义(P>0.05)。结论腺样体局部IL-6的高表达可能与分泌性中耳炎发病有关。
作者 张爱英 张勋 苏金柱
机构地区 河北省儿童医院耳鼻咽喉科 河北医科大学第三医院耳鼻咽喉科
出处 《听力学及言语疾病杂志》 CAS CSCD 北大核心 2011年第3期270-271,共2页 Journal of Audiology and Speech Pathology
关键词 分泌性中耳炎 腺样体肥大 白细胞介素-6
分类号 R764.21 [医药卫生—耳鼻咽喉科]
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参考文献14

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二级参考文献38

  • 1陈穗俊,梁象逢,郑亿庆,刘伟,许耀东,刘翔.白介素-2在分泌性中耳炎中的临床意义[J].中华耳科学杂志,2005,3(2):93-96. 被引量：16
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听力学及言语疾病杂志
2011年 第3期

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