摘要
本文采用培养的人胎儿胰岛组织移植治疗Ⅰ型糖尿病患者18例,其中脑内移植者10例,腹腔内移植者8例。脑内胰岛移植组显效者7例,已完全撤离胰岛素治疗达2～13个月,有效者2例,每日胰岛素剂量较移植前减少37和64％,病情控制良好,无效者1例。腹腔内胰岛移植组有效者6例,其中4例均在2～5个月内复发。无效者2例。研究结果初步表明,脑内胰岛移植治疗Ⅰ型糖尿病较腹内移植为优。
We treated 18 patients with I type diabetes mellltus by transplantation of human fetal pancreatic islet. Intracerebral intra-abdoninal transplantations were pentormed on 10 and 8 caces, Respectively 7 cases of intracerebral transplantation had significant effects without using insulin for 2 to 13 months. Insulin daily dosages of 2 cases had been reduced by 37% and 64% than before transplantation respectively, condition of illness werse controlled very well. 1 case was noneffective. 6 cases of intra-abdominal transplantation was effective. But 4 cases of them recured in 2 to 5 months. 2 cases were noneffective. The research results show that intracerebral pancreas islet rtansplantation treating I type diabetes mellitus is better than intra-abdominal transplantation.
出处
《潍坊医学院学报》
1990年第3期57-59,共3页
Acta Academiae Medicinae Weifang
关键词
糖尿病
胰岛
脑内移植
免疫
I type diabetes mellitus
pancreatic islet
intracerebral transplantation
immunologically privileged site
