摘要
目的探讨脑脊液置换联合地塞米松鞘内注射对蛛网膜下腔出血(SAH)的疗效。方法将确诊蛛网膜下腔出血的患者56例,随机划分治疗组(28例)和对照组(28例),治疗组在常规治疗基础上采取脑脊液置换术联合地塞米松鞘内注射治疗,对照组仅进行常规治疗,比较两组患者脑血管痉挛与脑积水发生率及病情转归。结果治疗组经过治疗,头痛、脑膜刺激征在短期内(4.78±2.56)d均明显好转,治愈好转率(85.7%)高于对照组(60.7%),且治疗期间缩短,治疗组和对照组脑血管痉挛发生率分别为10.2%、35.7%(P<0.05),治疗组和对照组脑积水发生率分别为7.1%、28.6%(P<0.05)。结论脑脊液置换联合鞘内地塞米松注射治疗组优于对照组,能迅速缓解临床症状,降低脑血管痉挛及脑积水发生率,减少并发症的发生。
Objective To discuss curative effect of the exchange of cerebrospinal fluid combined with intrathecal injection of dexamethasone on subarachnoid hemorrhage（SAH）.Methods Fifty six patients with SAH were randomly divided in treatment group（28 cases） and contrast group（28 cases）;the treatment group received the exchange of cerebrospinal fluid combined with intrathecal injection of dexamethasone based on the routine treatment;while the contrast group received the routine treatment alone.The cerebral vasospasm,incidence of hydrocephalus,and the outcome of the illness were compared.Results Headache and meningeal irritation of patients in the treatment group were significantly improved in the short term（4.78±2.56） days,the treatment period was shorter,the cure rate（85.7%） was higher than that of the contrast group（60.7%）.The incidence of cerebral vasospasm in the treatment group and the contrast group was 10.2% and 35.7%（P0.05）,respectively;the incidence of hydrocephalus in treatment group and contrast group was 7.1% and 28.6%,respectively（P0.05）.Conclusion The exchange of cerebrospinal fluid combined with intrathecal injection of dexamethasone is more effective for SAH as compared to the contrast group.It can quickly relieve symptoms and reduce the incidence of cerebral vasospasm and hydrocephalus and reduce the complications.
出处
《中华全科医学》
2011年第6期901-902,共2页
Chinese Journal of General Practice
关键词
蛛网膜下腔出血
脑脊液置换
地塞米松
疗效
Subarachnoid hemorrhage
Exchange of cerebrospinal fluid
Dexamethasone
Curative Effect
