摘要
目的研究人类免疫缺陷病毒(human immunodeficiency virus,HIV)感染病例流行特征。方法抽取330例首都医科大学附属北京佑安医院性病艾滋病临床诊疗中心收治的2003年1月至2007年12月确诊的获得性免疫缺陷综合征(acquiredimmuno deficiency syndrome,AIDS)患者为调查对象,回顾性分析HIV/AIDS患者HIV传播途径,HIV-1/乙型肝炎病毒(hepatitis Bvirus,HBV)/丙型肝炎病毒(hepatitis C virus,HCV)/梅毒共感染,艾滋病发病比例变化等流行病学资料。结果①随机选取诊疗中心收治的330例HIV/AIDS患者,其性传播途径和经血传播比例在2003至2007年分别为30%vs 60%、24.8%vs 75%、26.9%vs 70%、67.9%vs 20%、84.9%vs 10%。②HIV-1/HBV共感染患者比例2003至2007年分别为4%、10%、14%、21%、22%;而HIV-1/梅毒共感染患者比例为15%、5%、16%、23%、30%;HIV-1/HCV共感染患者比例为60%、62%、51%、18%、8%。③HIV/AIDS患者中AIDS患者比例逐年上升,由2003年的6.5%上升至2004年的9.5%、2005年的20%、2006年的25%和2007年的26.3%。结论①HIV的性传播途径与HIV-1/HBV、HIV-1/梅毒共感染比例均呈上升趋势,而经血传播途径及HIV-1/HCV共感染比例均呈下降趋势,北京地区HIV的主要传播途径由经血传播途径转变为性传播途径;②HIV/AIDS患者中AIDS患者比例有逐年上升趋势。
Objective To analyze the epidemic characteristics of HIV/AIDS cases. Methods The epidemiological data,including HIV transmission routes,HIV-1 co-infection with HBV/HCV/syphilis and the percentage of AIDS among HIV/AIDS cases diagnosed from Jan.2003 to Dec.2007 in AIDS clinic of Beijing You＇an Hospital,Capital Medical University,were analyzed retrospectively. Results ① Data of randomly selected 330 HIV/AIDS cases from AIDS Clinic of Beijing were used.Among the cases,the rates of infection via sexual transmission and via blood transmission from 2003 to 2007 were 30% vs 60%,24.8% vs 75%,26.9% vs 70%,67.9% vs 20%,84.9% vs 10%,respectively.② The percentage of HIV-1 co-infection with HBV were increasing from year2003 to 2007 were 4%,10%,14%,21%,22%,respectively;while co-infection with syphilis were 15%,5%,16%,23%,30%,respectively;the percentage of HIV-1 co-infection with HCV were 60%,62%,51%,18%,8%,respectively.③ The percentage of AIDS among HIV/AIDS cases tended to be increasing year by year,It increased from 6.5%（year 2003） to 9.5%（year 2004） and 20%（year 2005）,25%（year 2006）,26.3%（year 2007）. Conclusion ① Among the cases,there had been an alarming increase in the rates of infection via sexual transmission and co-infection with HBV/syphilis,while the rates of infection via blood transmission and co-infection with HCV had a rapid drop.Infection via sexual transmission tended to replace the blood transmission and is becoming the major route of transmission.② The percentage of AIDS among HIV/AIDS cases tended to be increasing year by year.
出处
《首都医科大学学报》
CAS
北大核心
2011年第2期182-185,共4页
Journal of Capital Medical University
基金
国家自然科学基金(30872226)
国家"十一五"传染病重大专项(2008ZX10001-006
2008ZX10001-001)
北京市属高等学校人才强教计划资助项目(PHR201007112)~~
