摘要
目的探讨盆腔浆液性腺癌的卵巢形态特点及其在盆腔浆液性腺癌发生中的意义。方法对43例浆液性腺癌进行分析,其中包括31例卵巢癌与12例腹膜癌,观察卵巢的大体与镜下形态以及合并的病变。结果 43例浆液性腺癌均有卵巢受累,35例(81.4%)为双侧性,42例累及多个脏器。大体观察,卵巢癌组与腹膜癌组卵巢表面有乳头与粘连的比率分别为65.3%与95.2%,切面实性的比率分别为35.2%与81.2%。镜下见卵巢癌与腹膜癌卵巢表面受累的比率分别为22.8%与66.7%,可见残存正常卵巢的比率为66.7%与100%。43例中6例合并子宫浆膜或卵巢子宫内膜异位,1例对侧卵巢考虑子宫内膜异位恶变,2例卵巢包涵腺体未见腺上皮的增生性改变。结论卵巢癌可能是盆腔浆液性腺癌多脏器受累的表现之一,卵巢癌与腹膜癌的卵巢存在很多相似与重叠形态,提示至少部分卵巢癌与腹膜癌有相似的来源,可能为继发性肿瘤。
Objective To study the morphologic characteristics of the ovary in pelvic serous adenocarcinoma,and to discuss its significance in the carcinogenesis.Methods Clinicopathologic data were analyzed in 43 cases of pelvic serous adenocarcinoma,including 31 cases of ovarian carcinoma and 12 peritoneal carcinomas.The macroscopic and microscopic features of the ovary and those of associated lesions were observed and investigated.Results The ovary involved by carcinoma was found in all of the 43 cases of pelvic serous adenocarcinoma,35 cases（81.4%） of which were bilateral.Carcinoma was spread into multiple organs except 1 case.On macroscopy,65.3% of ovarian cancer and 95.2% of peritoneal cancer had papillary or adherence on the surface of the ovary.35.2% of ovarian cancer and 81.2% of peritoneal cancer had solid cut surface of the ovary.On microscopy,ovarian surface involved by tumour was found in 22.8% of ovarian cancer and 66.7% of peritoneal cancer.Normal tissues in the remaining ovary were in 66.7% of ovarian cancer and 100% of peritoneal cancer,respectively.6 of 43 cases were associated with endometriosis lesion on the uteri serosa or the ovary.1 case was considered endometriosis canceration in the other side of ovary.None of the 2 cases of ovarian inclusion glands presented with proliferative changes.Conclusion Ovarian cancer may be a part of the multiple foci in pelvic serous adenocarcinoma.The morphological features of the ovary are similar or overlaying between the cases of ovarian cancer and peritoneal cancrer.It is suggusted that at least some cases of ovarian cancer and peritoneal cancer have the common origin,and may be secondary tumors.
出处
《诊断病理学杂志》
CSCD
2011年第2期85-88,共4页
Chinese Journal of Diagnostic Pathology
关键词
盆腔浆液性腺癌
卵巢
病理形态
Pelvic serous adenocarcinoma
Ovary
Pathologic morphologic features
