摘要
目的:探讨新生儿脑脊液(cerebrospinal fluid,CSF)胆红素测定的临床意义。方法:抽取试验组40例胆红素脑病患儿与对照组18例单纯高胆红素血症患儿相比较,均于入院时取血、CSF标本,将2组之间血未结合胆红素(unconjugated bilirubin,UCB)、CSF中UCB、血UCB与A比值(B/A)进行比较。结果:脑脊液胆红素含量与胆红素脑病的发生密切相关;脑脊液胆红素浓度与血清浓度无关。结论:CSF中UCB测定可作为胆红素脑病可靠指标,B/A作为胆红素毒性指标较血UCB更有意义,且血B/A与CSF中UCB有相关性。
Objective： To investigate the clinical significance of cerebraspinal fluid （CSF） bilirubin. Method ：Taking the test group and 40 patients with bilirubin encephalopathy alone control group, 18 patients with hyperbilirubinemia compared children were on admission blood, CSF samples of blood between the two groups did not bilirubin （unconjugated bilirnbin, UCB） ,CSF in the UCB, UCB and A blood ratio （B/A） were compared. Result： Bilirubin content of cerebrospinal fluid and is closely related to the occurrence of bilirubin encephalopathy;cerebrospinal fluid and serum bilirubin concentration independent of the concentration. Conclusion：Determination of CSF in the UCB can be used as a reliable indicator of bilirubin encephalopathy ,B/A as an index of bilirubin toxicity of UCB is more meaningful than the blood, and blood B/A and CSF were correlated in the UCB.
出处
《医学信息（中旬刊）》
2011年第5期1995-1996,共2页
Medical Information Operations Sciences Fascicule
关键词
新生儿
脑脊液
胆红素
Newborn
Cerebrosplnal fluid
Bilirubin
