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保存人羊膜联合自体角膜缘移植治疗陈旧性眼部烧伤 被引量:13

Transplantation of preserved human amniotic membrane for ocular surface reconstruction in severe chronic ocular chemical burn
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摘要 目的 观察羊膜移植 (AMT)在重建眼表面 ,治疗陈旧性眼部烧伤中的应用价值。方法 采用保存人羊膜联合自体角膜缘移植 (LT)治疗 15例 ( 15只眼 )。结果  15只眼中 ,12只眼眼表面重建成功 ,10只眼角膜透明或半透明 ,8只眼脱盲。结论 保存人羊膜无抗原性 ,具有抗炎、抑制新生血管及纤维化 ,阻止结膜源性组织再侵入的作用 ,采用保存人羊膜联合自体LT治疗陈旧性眼部灼伤 ,是一种有价值的方法 。 Objective To evaluate the therapeutic effects of amniotic membrane transplantation (AMT) for ocular surface reconstruction in severe chronic ocular chemical burn. Methods 15 eyes in 15 patients who had severe ocular surface disorder were treated with AMT and limbal transplantation(LT). Results Of 15 eyes,the epithelia healed stably without neovascularization in 12 eyes,there was corneal transparency or semitransparency in 10 eyes,and 8 eyes were without blindness. Conclusion Preserved amniotic membrane has the following characteristics:lacks antigenicity,is antiinflammatory,inhibits neovascularization and prevents the invasion of conjunctival tissue.The transplantation of preserved amniotic membrane and limbal graft is a valuable method for the treatment of severe chronic burn and should be studied extensively.
出处 《眼科研究》 CSCD 1999年第5期376-378,共3页 Chinese Ophthalmic Research
基金 河南省自然科学基金!资助 (基金编号 :9840 2 0 60 0 )
关键词 陈旧性 眼部灼伤 羊膜移植 角膜移植 chronic ocular chemical burn amniotic membrane transplantation keratoplasty
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