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结节性甲状腺肿合并甲状腺癌29例临床分析 被引量:13

Clinical Analysis of 29 Cases of Nodosity Thyromegaly Complicated by Thyroid Carcinoma
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摘要 目的:探讨结节性甲状腺肿合并甲状腺癌的治疗原则与措施,以及它们之间可能存在的相关性。方法:回顾分析医院自2005年1月至2009年8月接受手术治疗的术后病检证实为结节性甲状腺肿合并甲状腺癌的29例患者的临床资料,分析病例的临床及病理特点,进行对比研究。结果:所有接受手术治疗结节性甲状腺肿患者387例,其中29例合并甲状腺癌:甲状腺乳头状癌16例,甲状腺乳头状微小癌11例,滤泡性癌1例,髓样癌1例。29例患者中,25例术前彩超提示有沙粒样钙化,其中乳头状微小癌11例中,10例有沙粒样钙化,髓样癌1例有沙粒样钙化,滤泡性癌1例有沙粒样钙化,剩余16例甲状腺乳头癌,13例有沙粒样钙化。结论:结节性甲状腺肿患者,术前彩超提示有沙粒状钙化(≤2mm)者,要高度警惕合并甲状腺癌的可能,术前针吸细胞学检查和/或术中快速冰冻切片对手术方式的选择有指导意义,结节性甲状腺肿与甲状腺癌之间可能存在某种相关性。 Objective:To investigate the therapeutic principles and ways for the patients who had nodosity thyromegaly complicated by thyroid carcinoma, and the correlation between the nodosity thyromegaly and the thyroid carconima. Methods: The clinical date of 29 patients were analyzed retrospectively. Results:387 patients who had nodosity thyromegaly were admitted into the operation. Among them, there are 29 patients who have nodosity thyromegaly complicated by thyroid carcinoma: thyroid papillary carcinoma is 16;thyroid papillary microcarcinoma 11; thyroid follicular carcinoma 1; thyroid cephaloma 1. In 25 out of 29 patients, the gravel microcalcofication was showed by preoperative color Doppler ultrasound. The gravel microcalcification included the following patients: thyroid papillary microcarcinoma 10; thyroid paillary carcinoma13; thyroid cephaloma 1; thyroid follicular carcinoma 1. Conclusions:The gravel microcalcification(≤2mm)by preoperative color Doppter shows that there is the possibility that the nodosity thyromegaly may be complicated by the thyroid carcinoma. The cylology physical examination and the frozen section during operation contribute to the choice of pattern of operation. And there is some relationship between the nodosity thyromegaly and the thyroid carcinoma.
作者 童彦初
出处 《长江大学学报(自然科学版)》 CAS 2011年第3期142-144,6+5,共3页 Journal of Yangtze University(Natural Science Edition)
关键词 结节性甲状腺肿 甲状腺癌 沙粒样钙化 Nodosity thyromegaly Thyroid carcinoma Gravel microcalcification
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