摘要
目的：研究广州市肺癌危险因素，为进一步的肺癌危险因素监测提供依据。方法：１９９７ 年１６ 月采用问卷调查，对２５８ 例年龄范围在３０７４ 岁肺癌生存病例，按１ ∶１ 配对，调查了包括一般情况、生活居住环境、饮食习惯、生活方式、疾病及家族史等５ 个方面３５ 项１７３ 个问题。用相对危险度的近似估计值比值比来估计各危险因素与肺癌的联系强度，用Ｌｏｇｉｓｔｉｃ 回归模型做单因素和多因素分析筛选出专业上有意义的肺癌危险因素。结果：与肺癌发病有关的主要变量４ 个，分别为吸烟、精神压抑、呼吸系统疾病史、１０ 年前以煤为生活燃料。保护因素为体育锻炼、１０ 年前肉类月均消耗量高、１０ 年前动物油月均消耗量高、１０ 年前住房为木地板、喜欢酸性食品、良好的体质指数等６ 个因素。结论：吸烟和精神压抑是具有统计学意义的肺癌危险因素，良好的体质指数是肺癌的保护因素。
Objective:By study of the risk factors of lung cancer in Guangzhou,evidences for further monitoring of the risk factors were provided. Methods:A total of 258 male cases (age range from 30～74 years old) of lung cancer survivors were surveyed by questionnaire,matched 1∶1 with controls,between January to June, 1999 There were totally 5 sections,35 items and 173 questions in the questionnaire.Survey included general conditions,living environment,diet habit, living style,disease and family history,etc.Correlation power of all the risk factors and lung cancer was evaluated by the odd ratio (OR). Logistic regression model univariate and multivariate analysis were used to choose significant lung cancer risk factors on specialty. Results:Smoking,depression,a history of respiratory disease,coal as living fuel 10 years ago are 4 main variants relate to the genesis of lung cancer.Athletic exercise,high monthly meat consumption 10 years ago, high monthly animal oils consumption 10 years ago, favor of acid food, better body constitution are 6 protect factors. Conclusion:Smoking and depression are statistically significant lung cancer risk factors,better body constitution is the protect factor of lung cancer.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
1999年第5期535-537,共3页
Chinese Journal of Cancer
基金
国家"九五"攻关项目!(96 - 906 - 01- 01)
中山医科大学"211 工程"重点学科建设项目!(98073)
