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腺嘌呤核苷酸转位酶与细胞凋亡 被引量:3

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摘要 腺嘌呤核苷酸转位酶(adenine nucleotide translocase,ANT)是位于线粒体内膜上的一类转运蛋白,既能将细胞的产能和耗能过程耦联起来,也与线粒体膜通透性转换孔(mitochondrial permeability transition pore MPTP)密切相关,MPTP是位于线粒体内外膜之间的多蛋白组成的高导离子通道,它的开放可诱导细胞凋亡。所以ANT是一种能量转运和凋亡诱导的双重功能蛋白。本文主要就其与细胞凋亡的关系做一综述。
作者 李燕 宋耀明
出处 《西部医学》 2011年第5期984-986,共3页 Medical Journal of West China
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