摘要
目的总结应用单精子卵细胞质内注射（ICSI）治疗不孕症的临床效果。方法对34对男性因素、原因不明、受精障碍不孕患者采用GnRHa长周期促排卵方案，给有第一极体的卵细胞行单精子注射。结果34例34个治疗周期中，1例因反应不良取消。取卵数378个，注射卵数317（83．9％）个，正常受精卵231个（72．9％）卵裂228（98．3％）个，良好胚胎99（43．4％）个，平均移植胚胎数36个，临床妊娠12例（移植周期妊娠率为36.4％）。结论ICSI是治疗男性因素、原因不明、受精障碍等因素引起不孕症的一种切实可行的方法。
Objective To evaluate the efficacy of intracytoplasmic sperm injection (ICSI) in the treatment of infertility MethodsOvulation induction was accomplished with the use of GnRH agonist down-regulation combined with HMG/FSH stimulation in 34patients. Mamre oocytes with the tirst polar body were selected for ICSI. Results The total number of oocytes collected was 378,injected oocytes 317(83.9%), fertilized oocytes 231(72.9%), developed embryos 228(98.3%), embryos with good morphology 99(43.4%); Average number of embryo transfer was 3.6. The clinical pregnancies were achieved in 12 patients and the pregnancy rateof transtbr cycle was 35.3%. Conclusion ICSI would be the first choice for treatment of male infertility idiopathic infertility andfertilization failure with conventional IVF.
出处
《第一军医大学学报》
CSCD
1999年第4期343-344,共2页
Journal of First Military Medical University
