摘要
目的研究精神分裂症患者认知障碍与阴、阳性症状群的关系。方法将新入院且未经治疗的60例精神分裂症患者依据阴性症状量表(SANS)、阳性症状量表(SAPS)测定结果分为阳性症状群组(P组)和阴性症状群组(N组),另选择健康陪护者为对照组。对3组分别做韦氏记忆量表(WMS)和威斯康星卡片分类测验(WCST)检查,测定其认知障碍。结果 WMS检查显示,除100→1外,P组其他因子均明显优于N组(P<0.05);对照组理解因子显著优于P组(P<0.05),其他各因子则无统计学意义(P>0.05)。WCST检查显示:P组Rc、Re、Rpe三因子明显优于N组(P<0.05);P组Rc、Re和对照组比较有统计学意义(P<0.05),但两组Rpe、nRpe比较无统计学意义(P>0.05)。结论分裂症患者认知障碍与阴性症状群的关系明显较阳性症状群密切。
Objective ＂1o study the relationship between cognition deficit and positive, negative symptoms in patients with schizophrenia. Methods A total of 60 patients with schizophrenia were divided into the positive symptoms group（P group） and the negative symptoms group（N group）. The contrast group consisted of some healthy cases. WMS （Wechsler adult Memory Scale） and WCST （Wisconin Card Sorting Test） were used. Results The score of WMS in P group was significantly higher than that of N group （ P ~ 0.05）, The factor scores of WMS in the control group were equal to those of P group（ P ~0.05） except the understanding factor（ P 〈 0.05）. According to WCSW, the Rc, Re, and Rpe scores of P group were significantly higher than those of N group （ P ~0.05）,and there existed no significant difference between P group and the normal control group（ P ~0.05）. Conclusion In patients with schizophrenia, cognition deficit is closely related to negative symptoms.
出处
《山东医学高等专科学校学报》
2011年第2期133-135,共3页
Journal of Shandong Medical College
关键词
精神分裂症
认知障碍
阳性症状
阴性症状
Schizophrenia
Cognition deficit Positive
Positive symptom
Negative symptom
