摘要
目的:探讨氟喹诺酮类药物导致的不良反应发生的临床特点和分布情况。方法:回顾性分析我院2010年1月-9月收治的72例氟喹诺酮类药物出现不良反应患者的临床资料,并进行数据总结分析。结果:氟喹诺酮类药物不良反应男性发生率明显高于女性的发生率(P<0.05);38~58岁是氟喹诺酮类药物不良反应发生的主要年龄段,明显高于其他年龄段(P<0.05)。不良反应临床表现主要以神经系统为主;38~58岁年龄段不良反应发生时间和恢复时间均明显高于其他年龄段(P<0.05)。结论:应用氟喹诺酮类药物时要充分认识其不良反应发生情况,注意对可能发生的不良反应进行预防,降低不良反应的发生率。
Objective: To evaluate fluoroquinolone adverse reactions caused by the clinical characteristics and distribution. Methods: A retrospective analysis of 72 patients of our hospital from January 2010 1 - 9 months, they were treated adverse reactions of fluoroquinolones in patients with clinical data, and data were analyzed. Results: Fluoroqulnolone adverse reactions were significandy higher than the male rate of females ( P 〈 0.05 ) ; 38 - 58 years of age is adverse reactions of fluoroquinolones main age groups, significantly higher than other age groups ( P 〈 0.05). Clinical manifestations of adverse reactions based maiuly on the nervous system; 38 - 58 age group adverse reaction time and recovery time were significantly higher than other age groups ( P 〈 0.05). Conclusions: Fluoroquinolones should fully understand its adverse events, attention to the possible prevention of adverse reactions to reduce the incidence of adverse reactions.
出处
《内蒙古中医药》
2011年第7期29-30,共2页
Inner Mongolia Journal of Traditional Chinese Medicine
关键词
氟喹诺酮类药物
不良反应
临床特点
分布
fluoroquinolones
adverse reactions
clinical characteristics
distribution