摘要
目的回顾分析颌面部良性纤维骨病变的主要特点。方法分析1998年至2008年间在郑州大学口腔医学院口腔颌面外科就诊有病理证实的口腔颌面部肿物患者,研究患者的年龄、性别、临床和放射线特点、组织学诊断和治疗。结果 2018例患者中,良性纤维骨病变38例（女26例,男12例）,中位年龄24岁（11~62岁）,上颌略多于下颌,均表现为局部骨质隆起、质硬、无压痛及自发痛。组织学诊断：23例（60.53%）为骨纤维异样增殖、9例（23.68%）为骨化纤维瘤、6例（15.79%）为牙骨质化纤维瘤。均采用口内切口手术治疗,骨纤维异样增殖采用成形切除术,骨化纤维瘤和牙骨质化纤维瘤均完整摘除肿瘤。结论良性纤维骨病变多见于女性,发病年龄变化较大,但大多在20~30岁之间。纤维异样增殖症多见于上颌,骨化纤维瘤多见于下颌,牙骨质化纤维瘤上下颌机会均等。对良性纤维骨病变的正确诊断要依据病史、体检、放射线特点、术中发现及组织病理学。
Objective To analyse the principal characteristics of the cases of benign fibro-osseous lesions of the maxillofacial bones.Methords A retrospective review was made of all the pathology made in a service of department of oral and maxillofacial surgery of zhengzhou university stomatological college between 1998 and 2008.Analyse patients age,sex,clinical and radiological characteristics,histological diagnosis and treatment provided.Results A total of 2018 cases were performed during the study period.Of these,only 38 corresponded to benign fibro-osseous lesions（26 women and 12 men）.The mean patient age was 24 years（range 11~62 years）.The most frequent location was the upper maxilla.All the cases presented bulging of the cortical bone,with hard,no press and spontaneous pain.The histological diagnoses comprised 23（60.53%） fibrous dysplasia,9（23.68%） ossifying fibromas,6（15.79%） cementifying fibromas.All the pathients were operated via an intra-oral approach,the fibrous dysplasia cases operation is for cosmetic.Ossifying fibroma and cementifying fibromas cases surgical resection was carried out.Conclusions These lesions are more frequent in women than in men,the age at presentation is variable,and age distribution peaked in the second and third decades,in terms of lesion location,fibrous dysplasia is more common in the upper maxilla,ossifying fibroma is more frequently found in the mandible.While cementifying fibromas is equal occurrence in both jaws.The diagnosis of such lesions is established upon contrasting the data obtained from the anamnesis,physical examination,the radiological characteristics,the intraoperative findings and the histological study.
出处
《中国医药指南》
2011年第13期185-187,共3页
Guide of China Medicine
