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脂肪因子与胰岛素抵抗研究进展 被引量：2

Progress in research of adipokines and insulin resistance
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摘要 脂肪组织分泌的多种脂肪细胞因子,如肿瘤坏死因子(TNF)-α、白介素(IL)-6、单核细胞趋化蛋白(MCP)-1、瘦素和脂联素等均可介导或参与慢性炎症反应,导致胰岛素抵抗(IR)。本文综述脂肪因子与IR研究进展,简单介绍改善IR药物,为临床IR防治提供参考。 Adipose tissue secretes a variety of adipokines,such as tumor necrosis factor-α（TNF-α）,interleukin（IL）-6,monocyte chemoattractant protein（MCP）-1,leptin and adiponectin.These adipokines may mediate or participate in chronic inflammation reaction and lead to insulin resistance（IR）.This review summarizes the progress in research of adipokines,IR and their prevention and treatment.
作者 刘晔 王育璠 彭永德
机构地区 上海交通大学附属第一人民医院内分泌代谢科
出处 《世界临床药物》 CAS 2011年第5期266-270,共5页 World Clinical Drug
关键词 脂肪因子 胰岛素抵抗 慢性炎症 adipokines insulin resistance chronic inflammation
分类号 R977.15 [医药卫生—药品] R589 [医药卫生—内分泌]
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参考文献38

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同被引文献50

  • 1袁敏,韩莉,裴俊俊.葡萄籽提取物原花青素药理作用研究进展[J].中药材,2005,28(7):632-634. 被引量：20
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世界临床药物
2011年 第5期

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