摘要
目的:寻找肝肾不足型绝经后骨质疏松症的较佳治疗方法。方法:将105例患者随机分为观察组、对照组A和对照组B,每组35例。对照组A口服碳酸钙D3咀嚼片,对照组B口服碳酸钙D3咀嚼片和仙灵骨葆胶囊,观察组采用口服碳酸钙D3咀嚼片配合穴位埋线治疗,急性期穴取肾俞、肝俞、夹脊、委中等,缓解期取肾俞、肝俞等,半月1次,均治疗6个月。比较各组患者疼痛视觉模拟评分(Visual Analogue Scale,VAS)、骨密度、血清雌二醇(E2)的变化和临床疗效。结果:治疗3、6个月后各组VAS疼痛积分均较治疗前明显下降(均P<0.01),观察组、对照组B较对照组A的VAS疼痛积分下降明显(均P<0.001),观察组较对照组B下降更显著(均P<0.001)。治疗6个月后,观察组与对照组B的腰椎骨密度、血清E2含量与治疗前有显著提高(均P<0.01);治疗后组间比较,观察组与对照组B骨密度均优于对照组A(P<0.01,P<0.05),观察组血清E2水平高于对照组B、对照组A(均P<0.001),对照组B优于对照组A(P<0.001)。观察组总有效率91.4%(32/35)优于对照组A(57.1%,20/35),对照组B(82.9%,29/35)亦优于对照组A。结论:穴位埋线配合口服碳酸钙D3咀嚼片可减轻肝肾不足型绝经后骨质疏松症患者疼痛程度,提高患者的骨密度与血清E2水平,是一种较优方法。
Objective To explore the better treatment of postmenopausal osteoporosls of liver and kidney deficiency type. Methods One hundred and five cases were randomly divided into an observation group, a control group A and a control group B equally. In control group A, Calcichew Da tablets were taken with oral administration; in control group B, Calcichew IDa tablets and Xianling Gubao capsule were taken with oral administration. In observation group, Calcichew IDa tablets and acupoint catgut embedding were applied： Shenshu （BL 23）, Ganshu （BL 18）, Jiaji （EX-B 2） and Weizhong （BL 40） etc. were selected at acute stage; Shenshu （BL 23） and Ganshu （BL18 ） etc. were selected at remission stage, once every half a month and 6 months treatment in all. The Visual Analogue Scale（VAS）, bone mineral density（BMD）, estradiol （E2） and clinical effects were compared among groups. Results After 3 and 6 months treatment, the scores of VAS were reduced among groups （all P〈0.01） ; the reduction in observation group and eontrol group B was superior to that in control group A （all P〈0. 001）, and it was more obvious in observation group than that in control group B （both P〈0. 001）. After 6 months treatment, lumbar BMD and the serum level of E2 improved obviously in observation group and control group B （all P（0. 01）. The comparison among groups after treatment showed that the BMD in observation group and control group B was superior to that in control group A （P〈0.01 ,P〈0.05） ： the serum level of E2 in observation group was superior to that in control group B and control group A （both P〈0. 001）. and it m control group B was superior to that in control group a. The total effective rate was 91.4% （32 / 35） in observation group, superior to that in control group A （57. 1%, 20/35） ; and the total effective rate was 82. 9% （29 35） in control group B, superior to that in control group A. Conclusion Calcichew D3 tablets and acupoint catgut embedding therapy can relieve the pain caused by postmenopausal osteoporosis of liver and kidney deficiency, improve the bone mineral density and serum level of estradiol： in brief, it is the better method.
出处
《中国针灸》
CAS
CSCD
北大核心
2011年第4期315-319,共5页
Chinese Acupuncture & Moxibustion
基金
广西卫生厅立项科研项目:Z2008425
广西柳州市科技局科技攻关项目:2009021518
关键词
骨质疏松
绝经后
穴位埋线结扎
肝肾亏虚
Osteoporosis, Postmenopausal： Acupoint Ligat Thread Embed： Deficiency of the Liver and Kidney
