摘要
目的观察盆腔炎颗粒的抗炎镇痛作用。方法采用小鼠耳肿胀、大鼠足跖肿胀和棉球肉芽肿模型观察盆腔炎颗粒的抗炎作用;采用小鼠扭体反应和光热致痛观察盆腔炎颗粒的镇痛作用。结果盆腔炎颗粒明显抑制小鼠耳肿胀、大鼠角叉菜胶足肿胀和棉球肉芽肿;延长小鼠扭体潜伏期,减少扭体次数和提高光热致痛率。结论盆腔炎颗粒口服给药有显著抗炎和镇痛作用。
Objective To study anti-inflammatory and analgesic effects of granucle to pelvic inflammation.Methods The anti-inflammatory effects were studied by dimethylbenzene-induced swelling oar in mouse,carrageenin induced paw edema and tampon-induced proliferation in rats.The analgesic effects were studied by acetic acid-induced writhing and optothermal-induced pain in mice.Results Granule to pelvic inflammation significantly reduced swelling oar in mouse,paw edema and proliferation in rats;prolonged latency of writhing test,reduced the writhing number and improved optothermal-induced analgesia percentage.Conclusion Granule to pelvic inflammation has anti-inflammatory and analgesic effects.
出处
《安徽医科大学学报》
CAS
北大核心
2011年第4期362-365,共4页
Acta Universitatis Medicinalis Anhui
关键词
盆腔炎性疾病/中药疗法
川芎/治疗应用
大血藤/治疗应用
当归/治疗应用
牡丹皮/治疗应用
紫花地丁/治疗应用
镇痛
pelvic inflammatory disease/traditional chinese drugs therapeutic
ligusticum chuanxiong/therapeutic use
sargentodoxa cuneata/therapeutic use
angelica sinensis/therapeutic use
cortex moutan/therapeutic use
viola yedoensis/therapeutic use
analgesia
