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内镜黏膜下剥离术治疗食管黏膜病变 被引量:6

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摘要 目的:探讨内镜黏膜下剥离术(endoscopic submucosal dissection,ESD)治疗食管黏膜病变的应用价值。方法:Lugol′s碘染色确定病灶边界,内镜黏膜下剥离术完整剥离病灶并送检。切除成功率、手术时间、手术即刻及短期并发症及其发生率等纳入统计。结果:32例共33处食管黏膜病变接受治疗,30例共31处病变成功完成ESD治疗,ESD成功率93.9%(31/33)。2例患者病灶局部黏膜下注射后抬举不良且难以剥离转行手术治疗。ESD手术时间(自开始标记至完整剥离病变)55~125 min(平均85 min)。所有患者治疗过程中均有少量出血;2例食管黏膜内肿瘤剥离过程中出现皮下气肿,保守治疗成功,ESD穿孔发生率6.3%(2/32)。1例食管黏膜内癌合并皮肌炎的患者术后发生创面感染,术后第3天出现发热胸痛,抗感染治疗后6天恢复正常。成功实施ESD手术的30例患者平均住院8天,人均住院费用1.45万元人民币,术后每月随访1次,随访期3个月,创面基本愈合,无1例病变残留和复发。3例术后创面超过食管2/3周的患者,术后1个月就发生食管狭窄,经过平均2次球囊扩张后狭窄缓解。结论:ESD是治疗食管黏膜病变的有效方法,出血和穿孔是主要的近期并发症,剥离创面超过食管2/3周的患者则容易发生食管狭窄。
出处 《南京医科大学学报(自然科学版)》 CAS CSCD 北大核心 2011年第3期431-433,共3页 Journal of Nanjing Medical University(Natural Sciences)
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参考文献7

  • 1Ryu Ishihara, Hiroyasu.Iishi, Noriya Uedo, et al. Comparison of EMR and endoscopic submueosal dissection for en bloc resection of early esophageal cancers in Japan [J ]. Gastrointestinal Endoscopy, 2008,68 (6) : 1066-1072.
  • 2Gotoda T, Kondo H, Ono H, et al. A new endoscopic mucosal resection (EMR)procedure using a insulationtipped diathermic(IT)knife for rectal flat lesions: report of two cases [J]. Gastrointestinal Endoscopy,1999,50 (4) : 560-563.
  • 3Satoshi Ono, Mitsuhiro Fujishiro, Keiko Niimi, et al. Long-term outcomes of endoscopic submncosal dissection for superficial esophageal squamous cell neoplasms [J]. Gastrointestinal Endoscopy, 2009,70 (5) : 860-866.
  • 4杨传春,王亚东,伏亦伟.Lugol液染色诊断早期食管癌的临床价值[J].中华消化内镜杂志,2004,21(4):245-247. 被引量:13
  • 5董光宏,邹晓平,李兆申.内镜超声检查对胃及食管早期癌的诊断价值[J].中华消化内镜杂志,2005,22(3):185-187. 被引量:13
  • 6Oda I, Gotoda T, Hamanaka H, et al. Endoscopic submucosal dissection for early gastric cancer: technical feasibility, operation time and complications from a large consecutive series [J]. Digestive Endoscopy, 2005,17 ( 1 ) : 54-58.
  • 7周平红,姚礼庆,马黎丽,陈巍峰,徐美东,钟芸诗,张轶群,秦新裕.内镜黏膜下剥离术治疗食管病变[J].中国消化内镜,2007,1(9):14-17. 被引量:18

二级参考文献13

  • 1Yusuke Matsumoto,Hideo Yanai,Hiroshi Tokiyama,Makoto Nishiaki,Shingo Higaki,Kiwamu Okita. Endoscopic ultrasonography for diagnosis of submucosal invasion in early gastric cancer[J] 2000,Journal of Gastroenterology(5):326~331
  • 2Tanaeb S,Koizumi W,Mitomi H, et al.Clinical outcome of endoscopic aspiration mucosectomy for early stage gastric cancer[].Gastrointest Endosc.2002
  • 3Eguchi T,Gotoda T,Oda I,et al.Is endoscopic one-piece mucosal resection essential for early gastric cancer?[].Dig Endosc.2003
  • 4Gotoda T,Kondo H,Ono H,et al.A new endoscopic mucosal resectio(nEMR)procedure using a insulation-tipped diathermi(cIT)knife for rectal flat lesion:s report of two cases[].Gastrointest Endosc.1999
  • 5Oda I,Gotoda T,Hamanaka H,et al.Endoscopic submucosal dissection for early gastric cance:rtechnical feasibility,operation time and complications from a large consecutive series[].Dig Endosc.2005
  • 6Rosch T,Sarbia M,Schumacher B,et al.Attempted endoscopic en bloc resection of mucosal and submucosal tumors using insulated-tip knive:sa pilot series[].Endoscopy.2004
  • 7Gotoda T,Friedland S,Hamanaka H,et al.A learning curve for advanced endoscopic resection[].Gastrointest Endosc.2005
  • 8Tsunada S,Ogata S,Ohyama T,et al.Endoscopic closure of perforation caused by EMR in the stomach by application of metallic clips[].Gastrointest Endosc.2003
  • 9Minami S,Gotoda T,Ono H,et al.Complete endoscopic closure using endoclips for gastric perforation during endoscopic resection for early gastric cancer can avoid emergent surgery[].Gastrointest Endosc.2006
  • 10Fijishiro M,Ono H,Gotoda T,et al.Usefulness of Maalox for detection of the precise bleeding points and confirmation of hemostasis of gastrointestinal hemorrhage[].Endoscopy.2000

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