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喹硫平与利培酮治疗女性精神分裂症临床对照研究 被引量:3

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摘要 目的评价喹硫平与利培酮治疗女性精神分裂症的临床效果及安全性。方法选择精神分裂症女性患者124例,随机分为喹硫平组63例,利培酮组61例,分别采用喹硫平及利培酮治疗,在给药第2、4、6、8周后采用阳性症状量表(PANSS)评定两组患者治疗效果,采用副作用量表(TESS)评价两组患者毒副反应发生情况。结果给药第2、4、6、8周后两组间阳性症状量表总分、阳性分、阴性分及病例分降低率无差异,两组患者临床有效率无差异,治疗8周后,喹硫平组患者震颤、静坐不能、闭经发生率低于利培酮组,血清泌乳素异常率低于利培酮组。结论喹硫平及利培酮治疗女性精神分裂症具有相似的临床疗效,喹硫平对于女性泌乳素分泌影响较小,适合女性患者应用。
作者 吴德华
出处 《中国现代医生》 2011年第11期41-42,共2页 China Modern Doctor
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