摘要
目的:建立鱼腥草素钠栓有关物质的检查方法。方法:采用高效液相色谱法,色谱柱采用以十八烷基硅烷键合硅胶为填充剂;流动相为乙腈-水-10%四丁基氢氧化铵(75:125:0.6);检测波长283nm,流速为1.0ml/min。结果:通过辅料干扰试验,高温、光照、过氧化氢、酸和碱的破坏性试验等一系列试验证明了该方法的专属性和耐用性。结论:该方法能够较好控制本品有关物质。
Objective：To establish the method for relate substance of suppository. Methods：The method was carried by HPLC,The analytical column was C18 column; mobile pase： acetonitrile ： H2O ： 10% tetrabutylammonium hydroxide （75 ： 125 ： 0.6） ;The detection wavelength was 283mn ,The flow rate was 1.0ml/min. Results ：Pass disturb trial,high temprature.illuminaion,H2O2,acid destroy and alkali destroy trial and so on, Prove the method has good ecificity and serviceability. Conclusion：This method can control the ralate substance of this substance.
出处
《黑龙江医药》
CAS
2011年第2期225-227,共3页
Heilongjiang Medicine journal
关键词
鱼腥草素钠
栓剂
有关物质
Sodium Houttuyfonate
suppository
ralate substance
