摘要
随着人们生活水平的提高,痛风的发病率不断提高并且发病年龄出现低龄化趋势,寻找高效低毒的抗痛风药物成为当务之急。临床上常用来抗痛风的药物有秋水仙碱、非甾体类抗炎药、促肾上腺皮质激素、糖皮质激素等,近年来随着痛风分子发病机制的揭示,人们发现了治疗痛风的新靶点,利用这些新靶点进行抗痛风药物的研发,将会出现一些新型药物。该文对目前临床上常用的抗痛风药物及正在研发中的抗痛风药物进行了综述。
With the development of the living standard of the people,the incidence of gout is rising and the trend of incidence age of patients with gout gets younger.Developing high-effective and low-adverse anti-gout agents has been a priority of the agenda.Most commonly used anti-gout drug include colchicina,non-steroid anti-inflammatory drug,adrenocor ticotropic hormore,glucocorticoid and so on.With the revelation of the gout molecular pathogenesis,people will take advantage of these new targets to develop new anti-gout drug.Commonly used anti-gout drug and anti-gout drug in development are reviewed in this article.
出处
《安徽医药》
CAS
2011年第4期408-410,共3页
Anhui Medical and Pharmaceutical Journal
关键词
痛风
高效低毒
抗痛风药
gout
high-effect and low adverse
anti-gout drug
