摘要
蛇毒含多种生物活性成分,其中多数为酶类和活性肽类。随着蛇毒毒理学、药物学、生物化学和分子生物学的发展,蛇毒的许多组分已得到分离纯化和序列测定,并广泛应用于理论研究和临床应用。竹叶青蛇属是中国常见的毒蛇,近年来对其应用研究的报道颇多,就竹叶青属毒蛇的种类与分布,及其蛇毒组分的分离纯化、理化性质、分子克隆表达等方面的研究资料进行了概括和综述。
There are many kinds of biologically active substances which belong to the venom of snake and most of them are active enzymes and peptides.With the development of the snake venom toxicology,pharmacology as well as the biochemistry and molecular biology,many components of snake venom have been purified and sequenced,and some of them even have been used extensively in research and clinical applications.Trimeresurus are common snakes in China.In recent years,the studies about the application of it have been reported widely.In the paper,the data of the snake Trimeresurus including the kinds and distribution of it as well as the purification,the molecular cloning and expression were summarized.
出处
《生物学杂志》
CAS
CSCD
2011年第2期83-86,97,共5页
Journal of Biology
基金
重庆市教委项目(KJ090824)
关键词
竹叶青蛇属
蛇毒
纯化
Trimeresurus
snake venom
purification
