摘要
目的探讨胃黏膜高级别上皮内瘤变(highgrade intracpithelial neoplasia,HGIEN)的临床病理学特点和手术前后病理诊断误差的原因。方法对78例胃镜活检胃黏膜HGIEN的临床病理学资料进行回顾性分析。结果本组术前胃镜活检组织标本中未见黏膜肌层43例,可见黏膜肌层35例。均成功行手术根治,其中仅4例(5.12%)经手术证实符合HGIEN诊断;74例(94.88%)诊断为胃癌,27例(34.6%)为早期胃癌,47例(60.2%)为进展期胃癌。结论病理医生在诊断HGIEN病变时,应密切结合胃镜所见及临床主诉诊断,对组织标本进行多切片取材,认真鉴别癌与HGIEN的病变特征,以减少手术前后病理诊断的误差。
Objective To explore the clinicopathological characteristics of highgrade intraepithelial neoplasia（HGIEN） in gastric mucosa and to analyze the factors accounting for pathological diagnosis errors during preoperative and postoperative stages.Methods The clinicopathological data of 78 HGIEN patients was respectively analyzed.Results Of all the preoperative gastroscope biopsy specimens,muscular layer of mucosa was present in 35 cases and absent in 43.The radical operations on the 78 cases were successful,which showed that merely 4 cases were corresponding with HGIEN diagnosis.74 cases（94.88%） were diagnosed as gastric carcinoma,among whom,27 cases（34.6%） were confirmed as early gastric carcinoma,and 47cases（60.2%） as advanced gastric carcinoma.Conclusion In the diagnosis of HGIEN pathologic changes,doctors should reduce preoperative and postoperative pathological diagnosis errors by distinguishing the features of carcinoma from those of epitheliomatosis with study of section,and combining the findings obtained by gastroscope and clinical chief complaint（CC） and diagnosis.
出处
《临床误诊误治》
2011年第4期73-74,共2页
Clinical Misdiagnosis & Mistherapy
关键词
胃肿瘤
胃镜检查
活组织检查
诊断
鉴别
Stomach neoplasms
Gastroscopy
Biopsy
Diagnosis
differential
