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恩替卡韦治疗与慢性乙型肝炎患者外周血调节性T细胞的变化 被引量：3

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摘要 乙型肝炎病毒（HBV）感染是全球性的卫生问题,目前认为核苷类药物能够有效地控制HBV的复制,缓解及控制乙型肝炎的进展。其中具有代表性的药物恩替卡韦（ETV）是一种强有力的抗病毒药物,具有高效性及良好的耐受性的特点,
作者 宋春辉 杨斌 陈黎明 张纪元
机构地区 解放军第三○二医院肝病生物治疗研究中心
出处 《肝脏》 2011年第1期52-54,共3页 Chinese Hepatology
关键词 慢性乙型肝炎患者 恩替卡韦 调节性T细胞 外周血 核苷类药物 治疗 乙型肝炎病毒 抗病毒药物
分类号 R512.62 [医药卫生—内科学]
  • 相关文献

参考文献12

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二级参考文献12

  • 1Stoop JN,van der Molen RG,Baan CC,et al.Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection.Hepatology,2005,41:771-778.
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共引文献33

同被引文献19

  • 1张光文,姚新生,马世武,杨创国,于乐成,侯金林.慢性乙型肝炎患者外周血T淋巴细胞受体谱系分析及互补决定区3序列测定[J].中华肝脏病杂志,2006,14(1):23-28. 被引量：22
  • 2姚新生,马骊,温茜,邹红云,阮光萍,王小宁.监测TCR CDR3漂移的免疫扫描谱型分析技术的建立与鉴定[J].中华微生物学和免疫学杂志,2006,26(6):571-573. 被引量：33
  • 3l.iu H, Leung BP. CD4+ CD25+ regulatory T cells in health and disease [J]. Clin Exp Pharmacol Physiol, 2006, 33: 519- 524.
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  • 5Liang X, Bi S, Yang W, et al. Epidemiological serosurvey of hepatitis B in China-declining HBV prevalence due to hepatitis B vaccination [J]. Vaccine, 2009, 27: 6550-6557.
  • 6Martin-Gayo E, Sierra-Filardi E, Corhi AL, et al. Plasmacytoid dendritic cells resident in human thymus drive natural Treg cell development [J]. Blood, 2010,115 : 5366-5375.
  • 7Yu N, Li X, Song W, etal. CD4+CD25+CD127low/- T cells: a more specific Treg population in human peripheral blood [J]. Inflammation, 2012, 35: 1773-1780.
  • 8Trehanpati N, Sukriti S, Geffers R, et al. Gene expression pro- files of T cells from hepatitis B virus infected patients in acute and resolving phase [J]. J Clin Immunol, 2011, 31: 498-508.
  • 9Tran DQ, Shevach EM. Therapeutic potential of FOXP3+ reg- ulatory T cells and their interactions with dendritic cells [J]. Hum lmmunol, 2009, 70: 294-299.
  • 10Moore C, Sauma D, Reyes PA, etal. Dendritic cells and B cells cooperate in the generation of CD4+ CD25+ Foxps+ allogeneic T cells [J]. Transplant Proc, 2010, 42: 371-375.

二级引证文献20

肝脏
2011年 第1期

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