摘要
目的探讨老年垂体腺瘤患者的临床特征及手术疗效,为老年垂体腺瘤患者的临床诊治提供参考。方法回顾性分析2001年1月至2009年1月收治的46例老年垂体腺瘤患者(老年组)的临床资料,包括其临床表现、术后病理结果及术后并发症等,并与同期住院的91例非老年患者(对照组)相比较。结果与对照组相比,老年组患者病程明显较长,以头痛头晕为主诉、就诊时视野缺损、巨大腺瘤、术前合并其它疾病及无功能腺瘤者所占比例明显增高(P<0.05)。术后数月至数年多数老年患者出现腺垂体功能减退,甚至出现重度骨质疏松,严重影响生活质量。结论老年垂体腺瘤患者应早发现,及时治疗,以免延误治疗时机,影响术后患者的生活质量;术后应密切随访,定期监测内分泌功能。
Objective To enhance the levels of the clinical diagnosis and treatment of pituitary adenomas in the aged patients. Methods The clinical data of 46 aged patients with pituitary adenomas,who underwent surgery from January,2001 to January,2009,were analyzed retrospectively,including the disease course,clinical manifestation,immunohistochemical examination,complications before and after the operation and the data gained by following up. All the data were compared to those of 91 patients with pituitary adenomas,aged 45～59 years,serving as control group. Results The disease course was significantly longer and the occurrence rates of headache or dizziness,defect of visual field,macroadenoma,preoperative complication and nonfunctioning adenoma were significantly higher in the aged group than those in the control group（P0.05） . Most patients suffered from hypopituitarism and needed to be treated by the hormone and some patients even suffered from serious osteoporosis after the operation in the aged patients with pituitary adenomas. Conclusions Great attention should be pay to the aged patient with pituitary adenomas which should be diagnosed and treated as early as possible. The close following up and timely treatment of the postoperative complication is helpful to improving postoperative life quality in the aged patients with pituitary patients undergoing surgery.
出处
《中国临床神经外科杂志》
2011年第3期151-152,155,共3页
Chinese Journal of Clinical Neurosurgery
关键词
垂体腺瘤
老年患者
手术
诊断
Pituitary adenoma
The aged
Clinical feature
Diagnosis
Treatment
