摘要
目的探讨恩替卡韦联合地塞米松治疗慢性重型乙型肝炎的疗效。方法将128例慢性重型乙型肝炎患者随机分为治疗组64例，对照组64例，两组均给予同样的综合治疗，治疗组增加恩替卡韦和地塞米松治疗。结果治疗组血清HBV—DNA转阴率为91．5％（P〈0．01），丙氨酸氨基转移酶、血清总胆红素恢复正常率为67．2％、62．5％，总有效率为85．9％，病死率为14．1％，明显优于对照组（P〈0．05）。结论恩替卡韦联合地塞米松治疗慢性重型乙型肝炎疗效佳。
Objective To investigate the effect of entecavir combined with dexamethasone treatment on chronic severe hepatitis. Methods One hundred and twenty -eight patients with chronic severe hepatitis B were randomly divided into treatment group （64 patients） and control group （64 patients）, two groups were given the same comprehensive treatment, the treatment group received entecavir and dexam- ethasone in addition. Results The serum HBV - DNA negative rate was 91.5 % （ P 〈 0.01 ） in treatment group, the ALT, TBIL normal rate were 67.2%, 62.5%, total effective rate was 85.9%, mortality was 14.1% in treatment group, which were significantly better than control group（ P 〈0.05）. Conclusions Entecavir combined with dexamethasone treatment for chronic severe hepatitis B has good effect.
出处
《中国实用医刊》
2011年第9期8-9,共2页
Chinese Journal of Practical Medicine
