摘要
目的:探讨女性生殖器结核(FGTB)对体外受精-胚胎移植(IVF-ET)妊娠结局的影响。方法:选择2006年1月至2009年12月于河北医科大学第四医院生殖医学科行IVF-ET助孕的双侧输卵管梗阻患者,其中结核性输卵管梗阻(结核组)66例,非结核性输卵管梗阻(非结核组)240例,比较两组促性腺激素(Gn)用量、获卵数、受精率、优质胚胎率、种植率、临床妊娠率、流产率和分娩率的差异。结果:两组Gn用量、获卵数、受精率、优质胚胎率比较,差异无统计学意义(P>0.05)。结核组种植率、临床妊娠率、分娩率显著低于非结核组(P<0.05),流产率显著高于非结核组(P<0.05)。结论:结核性输卵管梗阻患者IVF-ET临床妊娠率降低,流产率增高,应重视女性生殖器结核对IVF-ET妊娠结局的影响。
Objective：To explore the influence of female genital tuberculosis on clinical outcome of fertilization and embryo transfer in vitro（IVF-ET）.Methods：The patients with bilateral tubal obstruction who experienced IVF-ET treatment from January 2006 to December 2009 in The Fourth Hospital of Hebei University were selected,including 66 cases of tubal obstruction with tuberculosis（TB group） and 240 cases of non-tuberculosis tubal obstruction（non-TB group）.The Gonadotropin（Gn） dosage,number of oocytes,fertilization rate,good quality embryos rate,implantation rate,clinical pregnancy rate,miscarriage rate anddelivery rate were compared between the two groups.Results：There were no significant differences in Gn dosage,number of oocytes,fertilization rate and good quality embryos rate between the two groups（P〈0.05）.The implantation rate,clinical pregnancy rate,delivery rate were significantly lower in TB group than those in non-TB group（P〈0.05）,miscarriage rate was significantly higher in TB group than that in non-TB group（P〈0.05）.Conclusions：For tuberculosis tubal obstruction patients,the clinical pregnancy rate of IVF-ET is decreased and abortion rate is increased,so more cautions should be paid to female genital tuberculosis.
出处
《实用妇产科杂志》
CAS
CSCD
北大核心
2011年第3期197-200,共4页
Journal of Practical Obstetrics and Gynecology
基金
河北省医学科学研究重点课题计划(编号:20090464)
关键词
女性生殖器结核
输卵管梗阻
体外受精-胚胎移植
临床妊娠率
Female genital tuberculosis
Tubal obstruction
In vitro fertilization-embryo transfer
Clinical pregnancy rate
