摘要
目的完善血瘀证目征肉眼计分方法,并编制以血瘀证目征为主的血瘀证定量诊断方程。方法 对544例(非血瘀组261例,血瘀组283例)患者目征改变,采用计算机色度原理进行定量分析并通过运算编制目征定量诊断血瘀证判别方程,对382例(非血瘀组97例,血瘀组285例)患者进行验证,计算血瘀证目征计算机判别方程的敏感性及特异性。比较目征计算机积分及肉眼积分,采用百分位法计算正常参考值。结果 目征各观察指标与血瘀证有正相关性,目征计算机计分方法的特异度83.5%,诊断敏感度89.8%,准确率88.2%,正确指数0.733。计算机目征积分与肉眼积分两种方法在非血瘀证及血瘀证轻、中、重度比较差异均有统计学意义(P<0.01),肉眼计分方法的正常参考值<15分。结论 目征计算机判别方程对血瘀证诊断有较高的特异性及敏感性,肉眼积分方法仍被证实可用于血瘀证诊断。
Objective To make out a computerized formula to diagnose eye＇s signs of blood-stasis syndrome（BSS）,and to improve the previous diagnostic methods by naked eyes.Methods The formula was created by detecting and analyzing the changes of eye＇s signs in 544 patients（261 of non-BSS and 283 of BSS） quantitatively,adopting computer＇s color scale principle.And the sensitivity,specificity and accuracy of the formula were verified in 382 patients（97 non-BSS and 285 of BSS）.The computerized integral was compared with the naked eye integral,and the normal reference value was calculated with percentile.Results Various observatory indices of eye＇s sign were positively correlated with BSS.The specificity of the computerized method was 83.5%,and the diagnostic sensitivity was 89.8%,the accuracy 88.2%,and the correct index 0.733.Comparisons between the computerized integral method and the naked eye integral method showed significant difference in patients of non-BSS or of BSS in various degrees（including mild,moderate and severe）（P0.01）.The reference value of the naked eye method was below 15.Conclusion The computerized formula of eye＇s signs has higher specificity and sensitivity in the diagnosis of BSS,while the naked eye integral method is proved to be useful.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
2011年第3期319-322,共4页
Chinese Journal of Integrated Traditional and Western Medicine
基金
国家中医药管理局资助课题(No.2003ZL35)
关键词
血瘀证目征
肉眼积分
计算机积分
eye＇s signs of blood stasis syndrome
integral by naked eyes
integral by computer
