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多发性硬化病因及发病机制的研究进展 被引量:3

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摘要 多发性硬化(multiple sclerosis,MS)是中枢神经系统(central nervolls system,CNS)炎性、多灶性、脱髓鞘性疾病,至今病因未明,虽然已有众多的研究揭示出比较明确的病理变化,但由于遗传因素、多种变异性及漫长的亚临床阶段使得大量的流行病学调查难以进行,进而也影响其发病机制的确定。
出处 《河北医科大学学报》 CAS 2011年第3期364-366,共3页 Journal of Hebei Medical University
基金 福州市科技局立项支持项目(2008-S-90)
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  • 1HEMMINKI K,LI X,SUNDQUIST J,et al.Risk for multiple sclerosis in relatives and spouses of patients diagnosed with autoimmune and related conditions[J].Neurogenetics,2009,10(1):5-11.
  • 2SADOVNICK AD,ARMSTRONG H,RICE GP,et al.A population-based study of multiple sclerosis in twins:update[J].Ann Neurol,1993,33(3):281-285.
  • 3SADOVNICK AD.European Charcot Foundation Lecture:the natural history of multiple sclerosis and gender[J].J Neurol Sci,2009,286(1-2):1-5.
  • 4ALONSO A,JICK SS,OLEK MJ,et al.Recent use of oral contraceptives and the risk of multiple sclerosis[J].Arch Neurol,2005,62(9):1362-1365.
  • 5CHALLONER PB,SMITH KT,PARKER JD,et al.Plaque-associated expression of human herpesvirus 6 in multiple sclerosis[J].Proc Natl Acad Sci USA,1995,92(16):7440-7444.
  • 6SOLDAN SS,BERTI R,SALEM N,et al.Association of human herpes virus (HHV-6)with multiple sclerosis:increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA[J].Nat Med,1997,3(12):1394-1397.
  • 7ALVAREZ-LAFUENTE R,DE LAS HERAS V,BARTOLOM M,et al.Relapsing-remitting multiple sclerosis and human herpesvirus 6 active infection[J].Arch Neurol,2004,61(10):1523-1527.
  • 8WANDINGER K,JABS W,SIEKHAUS A,et al.Association between clinical disease activity and Epstein-Barr virus reactivation in MS[J].Neurology,2000,55(2):178-184.
  • 9DELORENZE GN,MUNGER KL,LENNETTE ET,et al.Epstein-Barr virus and multiple sclerosis:evidence of association from a prospective study with long-term follow-up[J].Arch Neurol,2006,63(6):839-844.
  • 10LEVIN LI,MUNGER KL,RUBERTONE MV,et al.Temporal relationship between elevation of epstein-barr virus antibody titers and initial onset of neurological symptoms in multiple sclerosis[J].JAMA,2005,293(20):2496-2500.

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