摘要
目的：探讨放射性微粒与化疗栓塞在肝动脉灌注化疗栓塞术（tsanscatheter arterial chemoembolization,TACE）中的疗效是否有差异进行Meta分析,旨在明确放射性微粒是否能够提高TACE疗效。方法：网络检索1990~2010年有关数据库并辅以手工检索已有的参考文献,对纳入研究的文献提取原始数据,采用RevMan Manager 4.2软件进行Meta分析,计算合并RR值及95%可信区间（95%CI）。结果：对于控制肿瘤体积,放射性微粒与化疗栓塞在TACE术中的疗效差异无统计学意义;1年期生存率,放射性微粒疗效优于化疗栓塞,差异有统计学意义。结论：与化疗栓塞相比,放射性微粒栓塞不能提高肿瘤的应答,但能提高1年期生存率。
Objective：To investigate the difference of the curative effects between microspheres embolization and chemoembolization in tsanscatheter arterial chemoembolization（TACE） by the meta-analysis in order to confirm whether radiomicrospheres increase the efficacy of TACE.Methods：The relevant databases in internet network were retrieved.The original data from the literature included in the study were extracted and performed the meta analysis by software RevMan Manager 4.2.The combined RR and 95% CI were calculated.Results：The efficacy of controlling tumor volume by microspheres embolization and chemoembolization in TACE had no statistical difference.In 1-year survival rate,microspheres embolization was better than conventional chemoembolization with statistical difference.Conclusion：Compared to conventional chemoembolization,microspheres embolism can not increase the tumor response,but can increase the 1-year survival rate.
出处
《现代医药卫生》
2011年第7期972-974,共3页
Journal of Modern Medicine & Health
