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喹硫平与奥氮平对女性分裂症患者血糖和血脂代谢的影响 被引量:5

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摘要 目的比较喹硫平和奥氮平对女性分裂症患者糖代谢、血脂代谢的影响。方法选择住院治疗的女性精神分裂症患者,随机分成两组,一组使用喹硫平治疗,另一组使用奥氮平治疗,观察8周,分别于治疗前、治疗的2、4、6、8周末测定血糖和血脂(胆固醇、低密度脂蛋白、高密度脂蛋白)浓度,对所得数据进行统计学处理。结果两组患者在治疗4周以后均出现血糖、血脂升高的病例,8周以后与治疗前血糖升高无显著差异(P>0.05);血脂升高差异性显著(P<0.05),但两组间无显著差异(P>0.05);血糖、血脂升高与药物剂量无明显相关性(P>0.05)。结论喹硫平和奥氮平对女性精神分裂症患者的血糖、血脂代谢均有明显的影响,临床工作中要加以重视。
出处 《齐齐哈尔医学院学报》 2011年第1期39-40,共2页 Journal of Qiqihar Medical University
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