摘要
T-2毒素是由多种镰刀菌产生的单端孢霉烯族化合物中毒性较强的一种毒素,广泛存在于谷物和谷类食品中。经食物连续摄入T-2毒素会对人类和动物的健康造成潜在危害。目前,T-2毒素对人和动物健康的影响受到了社会的广泛关注,已成为毒理学领域研究的热点课题之一。在综述了T-2毒素的生物转化、代谢途径及其毒理学效应与机制基础上,对现有研究的不足和今后的研究方向进行了讨论,特别是在T-2毒素的精确分析检测和毒理学研究系统化等方面展开探讨。
T-2 toxin belongs to a large group of trichothecene mycotoxins produced by various Fusarium molds.It is widely scattered in cereals and cereal,which can cause human and animal diseases.Concerning on its threat to the health of human and animals,T-2 toxin has been paid more attention.In this paper,recent advances in the toxicity of T-2 toxin are reviewed,including the biotransformation,metabolic pathways,the toxicological effects and the toxicological mechanisms of T-2 toxin.In addition,the present problems in the recent studies and the developing trend in research of T-2 toxin are discussed.
出处
《生态毒理学报》
CAS
CSCD
2011年第2期121-128,共8页
Asian Journal of Ecotoxicology
基金
国家基金委青年基金项目(No.201037004)
