摘要
目的：探讨利尿剂对稳定型心绞痛（ Ｓ Ａ Ｐ）患者运动功能的影响。方法：将４０例 Ｓ Ａ Ｐ患者随机分为对照组和治疗组。对照组给予安慰剂，治疗组给予双氢克尿噻５０ ｍ ｇ 加氨苯喋啶５０ ｍ ｇ 每日１次，疗程１周。观察治疗前后最大氧耗量（ Ｖ Ｏ２ｍ ａｘ）的变化。结果：对照组服药前后 Ｖ Ｏ２ｍ ａｘ 分别为（１００．２８±３４．６４）、（１０６．３４±３６．５６）， Ｐ ＞ ０．０５。治疗组服药前后 Ｖ Ｏ２ｍ ａｘ 分别为（１１２．３４±３５．３８）、（１６６．３２±３６．４４）， Ｐ ＜ ０．００１。服药后两组 Ｖ Ｏ２ｍ ａｘ 分别为（１０６．３４±５６．５６）、（１６６．３２±３６．４４），有极显著性（ Ｐ ＜ ０．００１）。结论：利尿剂可明显改善 Ｓ Ａ Ｐ患者的运动功能。
Objective:To explore the effects of diuretic on maximum oxygen consumption (VO 2max) of stable angine pectoris.Method:Twenty patients with stable angine pectoris used placebo in group A,20 patient with stable angine pectoris used hydrochlorothiazide 50 mg 1/d+triamterene 50 mg 1/d for 7 days in group B.Before treatment and 7 days after the treatment assessed VO 2max respectively.Result:Before and after the treatment in group A VO 2max were ( 100.28 ± 34.64 ) and ( 106.34 ± 36.56 ) respectively which were no significant difference (P> 0.05 ).In group B VO 2max were ( 112.34 ± 35.28 ) and ( 166.32 ± 36.44 ) respectively which were significant statiscal difference (P< 0.001 ).After treatment the VO 2max had remarkablely significant difference between two groups (P< 0.001 ).Conclusion:Diuretic treatment may be remarkable improvement exercise performance of patients with stable angina pectoris.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
1999年第8期349-351,共3页
Journal of Clinical Cardiology
关键词
稳定型
心绞痛
利尿剂
运动试验
氧消耗
Angina pectoris Diuretic Exercise test Oxygen consumption
