摘要
目的通过对2型糖尿病伴高血压患者下肢血管的彩色多普勒超声检查,认识2型糖尿病伴高血压下肢动脉病变情况,为临床诊断和治疗提供依据。方法将2型糖尿病病人共70例,分成单纯糖尿病组(35例)和2型糖尿病伴高血压组(35例);另选取35例健康者作为对照。对受试者行双下肢动脉血管超声多普勒检查,观察双下肢股动脉、腘动脉、胫后动脉、足背动脉,记录每个受试者双下肢股动脉和腘动脉内膜中膜厚度及斑块大小、回声、分布情况,以及血流动力学指标。结果单纯糖尿病组及2型糖尿病伴高血压组下肢动脉斑块发生率均明显高于对照组(P<0.05),单纯糖尿病组斑块发生率明显低于2型糖尿病伴高血压组(P<0.05);与对照组比较,单纯糖尿病组及2型糖尿病伴高血压组的股动脉、腘动脉、足背动脉血流峰值流速降低,搏动指数增加(P<0.05)。结论应用彩色多普勒能探测到糖尿病伴高血压病人下肢动脉粥样硬化,二维图象主要表现为双下肢动脉内膜中膜厚度不规则增厚、斑块形成,尤以远端小动脉为主;彩色多普勒显示股动脉、腘动脉、足背动脉血流峰值流速降低,搏动指数增加。
Aim We examined patients with type-2 diabetes mellitus（T2DM） and hypertension using color Doppler ultrasound to observe the characteristics of atherosclerosis in lower artery.It would provide a theory for lower vascular disease prevention in patients with T2DM and hypertension. Methods 70 T2DM patients were divided into two groups： 35 type 2 diabetes without hypertension and 35 type 2 diabetes with hypertension,35 people in the control group received lower extremities vascular Doppler ultrasonography test.It included both lower extremities femoral artery,popliteal artery,posterior tibial artery and dorsalis pedis artery.The intimal-media thickness（IMT） value,plaque size,resonance,distribution and haemodynamics index of every subjects were recorded. Results Plaque of lower extremities in type 2 diabetes without hypertension and type 2 diabetes with hypertension were higher than the controls（P0.05）.The plaque incidence rate and IMT in group type 2 diabetes without hypertension were much lower than group type 2 diabetes with hypertension（P0.05）.Compared with the controls,the femoral artery,popliteal artery,arteria dorsalis pedis peak value flow rate cut down in the type 2 diabetes without hypertension and type 2 diabetes with hypertension group（P0.05）. Conclusion It can detect the characteristics of atherosclerosis in lower artery in patients with type 2 diabetes mellitus（T2DM） and hypertension by color Doppler ultrasound.In the two-dimensional images of the performance of the lower extremities artery IMT-irregular thickening,plaque formation,particularly the main artery distal small;Color Doppler showed femoral artery,popliteal artery,dorsalis pedis artery peak velocity slowed down,pulsatility index（PI）raised.
出处
《中国动脉硬化杂志》
CAS
CSCD
北大核心
2010年第12期972-974,共3页
Chinese Journal of Arteriosclerosis
基金
湖南省教育厅资助项目(10C1182)
关键词
彩色多普勒超声
2型糖尿病
高血压
下肢动脉病变
Color Doppler Ultrasound
Type-2 Diabetes Mellitus
Hypertension
Lower Extremities Artery
