摘要
目的：探讨早产合并临床绒毛膜羊膜炎时母血和脐血中细胞因子的变化。方法：应用ＥＬＩＳＡ法测定３１例早产合并临床绒毛膜羊膜炎孕妇（Ａ组）外周血和脐血中肿瘤坏死因子（ＴＮＦα）、白细胞介素６（ＩＬ６）和白细胞介素８（ＩＬ８）含量，并以３５例早产孕妇作对照（Ｂ组）。结果：Ａ组母血中ＴＮＦα、ＩＬ８均显著高于Ｂ组（Ｐ＜００５），脐血中ＩＬ６显著高于Ｂ组（Ｐ＜００２），母血中ＩＬ６，脐血中ＴＮＦα和ＩＬ８在Ａ、Ｂ两组中无显著性差异。结论：早产合并临床绒毛膜羊膜炎时细胞免疫功能增强。
Objective: To investigate the change of cytokines of maternal and umbilical cord serum in preterm labor with clinical chorioamnitis. Methods: 31 women with chorioamnitis between 29 and 36 weeks gestation( group A) were studied and 35 women without chorioamnitis were delivered between 28 and 36 weeks gestation (group B) as control, TNFIL6 and IL8 were measured by Enzymelinked immunosorbent assay. Results: TNF and IL8 concentrations in maternal sera in group A were significantly higher than those in group B(P<0.05) and IL6 concentrations in umbililcal cord sera in group A were significantly higher than that in group B(P<0.02), no significant difference in maternal IL6, umbilical cord TNF and IL8 concentrations were noted in both groups. Conclusion: For patients with preterm labor and clinical chorioamnitis the cellmediated immunity is activated.
出处
《中国免疫学杂志》
CAS
CSCD
北大核心
1999年第7期315-316,共2页
Chinese Journal of Immunology
