摘要
目的探讨喉部小细胞神经内分泌癌临床的特征及诊治方法。方法总结分析1例喉部小细胞神经内分泌癌患者的临床资料并复习相关文献。结果本文中患者肿瘤位于声门上,术前已有远处转移,采取手术加放疗及化疗等综合治疗,术后随访2个月局部无复发。结论喉部小细胞神经内分泌癌临床上罕见,其恶性程度高,极易发生远处转移,早期诊断、综合治疗有利于提高患者生存率,改善预后。
Objective To study the clinical characteristics,diagnosis and treatment of small cell neuroendocrine carcinoma（SCNEC） of larynx.Methods Clinical data of one patient suffering from laryngeal SCNEC was analyzed,and the literature was reviewed.Results The laryngeal tumor was located in the supraglottic region.Due to preoperative systemic metastasis,the patient was given conservative resection of the tumor,combined with postoperative radiotherapy and chemotherapy.No local recurrence occurred two months after operation.Conclusion Laryngeal SCNEC is very rare and highly aggressive.Dissemination should be considered at initial diagnosis of SCNEC.Surgery combined with chemo/radiotherapy might be effective to improve median survival of the patients.
出处
《中国耳鼻咽喉颅底外科杂志》
CAS
2010年第6期434-437,共4页
Chinese Journal of Otorhinolaryngology-skull Base Surgery
关键词
小细胞神经内分泌癌
喉部肿瘤
诊断
治疗
Small cell neuroendocrine carcinoma
Larynx
Diagnosis
Treatment
