摘要
目的探讨发生胎儿生长受限后并发子痫前期的高危因素及围产儿结局，了解其·】盏床特征。方法对186例胎儿生长受限的患者进行回顾性分析。根据发生胎儿生长受限后有无并发子痫前期分为：发生胎儿生长受限后并发子痫前期组（32例）和胎儿生长受限未合并子痫前期组（154例）进行比较。结果发生胎儿生长受限后并发子痫前期组的分娩孕周显著早于胎儿生长受限未合并子痫前期组（t=3．695，P〈0．001）；围产儿体重显著低于未合并子痫前期组（t=3．950，P〈0．001）；新生儿窒息的发病率高于未合并子痫前期组（χ2=6．124，P=0．013）；诊断胎儿生长受限的孕周早于未合并子痫前期组（Wald=6．513，P=0．012）。结论早发型胎儿生长受限可能是胎儿生长受限孕妇易并发子痫前期的危险因素，发生胎儿生长受限后并发子痫前期的围产儿预后较差，因此应积极预防，早期发现，及时干预。
Objective To investigate risk factors of fetal growth restriction （FGR） complicated with preeclampsia and perinatal outcomes. Methods The clinical data of 186 pregnant women with FGR complicated with/without preeclampsia were retrospectively analyzed. They were divided into two groups according to whether FGR was complicated with preeclampsia or not： FGR complicated with preeclampsia group （n = 32） and FGR not complicated with preeclampsia group （n = 154）. Results In FGR complicated with preeclampsia group ,the gestational age of the neonates was significantly younger than that of neonates born by those pregnant women with FGR not complicated with preeelampsia （t = 3. 695, P 〈 0. 001 ）, and perinatal body weight was significantly lower than that born by pregnant women with FGR not complicated with preeclampsia （ t = 3. 950, P 〈 0. 001 ）. The incidence rate of neonatal asphyxia in FGR complicated with preeclampsia group was higher than that in FGR not complicated with preeclampsia group （X2 =6. 124, P =0.013）. The gestational weeks when FGR was diagnozed in FGR complicated with preeclampsia group was earlier than that in FGR not complicated with preeclampsia group （ Wald = 6. 513, P = 0. 012 ）. Conclusion Early-onset FGR may be a high-risk factor that the pregnant woman with FGR would develop preeclampsia. The outcomes of perinatal infants born by those pregnant women with FGR complicated with preeelampsia are generally poorer. So some measures should be adopted in order to prevent actively, identify early and intervene timely FGR complicated with preeclampsia.
出处
《中国妇幼健康研究》
2011年第2期183-185,共3页
Chinese Journal of Woman and Child Health Research
关键词
子痫前期
胎儿生长受限
围产儿结局
危险因素
preeclampsia
fetal growth restriction （FGR）
perinatal outcome
risk factor
