摘要
目的观察加味佛手散水提取物对实验性原发性痛经的影响。方法采用缩宫素诱发小鼠原发性痛经模型和离体子宫平滑肌痉挛,以小鼠扭体潜伏期、扭体次数,离体子宫平滑肌收缩幅度和频率为指标,评价加味佛手散对原发性痛经治疗作用。结果加味佛手散可显著延长缩宫素诱发小鼠扭体反应的潜伏期,减少扭体反应次数,与模型组比较差异有统计学意义;降低缩宫素引起离体子宫收缩的幅度,减少收缩频率,与空白对照组比较差异有统计学意义。结论加味佛手散对缩宫素诱发小鼠的原发性痛经有显著的治疗作用。
Objective：To observe the therapeutic effect of the water extract of Modified Foshou Powder on primary dysmenorrhea.Methods：The primary algomenorrher model and the convulsion of uterus smooth muscle were induced by oxytocin in mice.These observe indices including the wring body latency period,the wring body times,the isolated uterus contraction amplitude and the isolated uterus frequency were evaluate the Modified Foshou Powder effect on primary dysmenorrhea.Results：After treatment with Modified Foshou Powder,the latency periods were lengthen and the times were shorten.Meanwhile,the contraction amplitude and the frequency were reduced.There were significant differences in these indices between the treatment group and the model group.Conclusion：Modified Foshou Powder has remarkable therapeutic effect on primary dysmenorrheal in mice.
出处
《中国中医急症》
2011年第4期601-602,共2页
Journal of Emergency in Traditional Chinese Medicine
基金
河北省秦皇岛市科技局资助项目(2010-1-87)
关键词
加味佛手散
原发性痛经
水提取物
缩宫素
Modified Foshou Powder
Primary dysmenorrhea
Water extraction
Oxytocin
