1Gillings D.History of clinical research:The future and promise of the 21st century medicine[R/OL].[2009-12-09].hnp://www.youtube.com/watch?v=PsrwsRhCcrY&NR=1.
2Association of American Medical Colleges Breaking the scientific Bottleneck.Clinical research:A national call to action[EB/OL].(1999-11)http://www.umassmed.edu/uploadedfiles/NationalCalltoAction.pdf.
3NIH.The NIH Roadmap for medical research[EB/OL].(2003-10-01) http://nihroadmap.nih.gov.
4Burke MA,de Francisco A,Matlin SA.Global forum for health research:Monitoring financial flows for health research 2004[EB/OL].(2004)http://www.globalforumhealth.org/Media-Pubhcations/Publications/Monitoting-Financial-Flows-for-Health-Research-2004.
5Krall R.U.S.clinical research.Presentation at the Institute of Medicine Workshop on Transforming Clinical Research in the United States[R].Washington D.C.October7-8,2009.
6Tufts Center for the Study of Drug Development.Impact report:Current investigator landscape poses a growing challenge for sponsors[EB/OL].(Jan/Feb,2009) http://csdd.tufts.edu/reports/description/ir_summaries.
7English R.Lebovitz Y,Giffin R.Transforming clinical research in the United States:Challenges and opportunities[M].Washington D.C.:The National Academy Press,2010.
8Institute of Medicine.Learning what works best:The nation's need for evidence on comparative effectiveness in health care[EB/OL].Washington D.C.(Sep,2007) http://www.iom.edu/~/media/Files/Activity%20Files/Quality/VSRT/ComparativeEffectivenessWhitePaperESF.pdf.
9McGlynn EA,Asch SM,Adams J,et al.The quality of health care delivered to adults in the United States[J].N Engl J Med,2003,348(26):2635-2645.
10Califf RM.ACS and acute heart failure models.Speaker presentation at the Institute of Medicine Workshop on Transforming Clinical Research in the United States[R].Washington D.C.October7-8,2009.