摘要
目的探讨同型半胱氨酸对急性脑梗死临床预后的影响。方法选择湘西自治州人民医院2007年12月至2009年12月急性脑梗死患者150例,根据入院24h内血浆同型半胱氨酸水平是否升高,把上述患者分为观察组和对照组。采用美国国立卫生研究院卒中量表(NIHSS)和BI指数对两组患者入院时、发病后不同时间进行神经功能缺损和日常生活活动能力评分;观察两组患者1年内脑梗死复发情况。结果观察组入院后4周和24周神经功能缺损和日常生活活动能力评分分别对照组同期比较,差异有统计学意义(P<0.05);两组脑梗死复发率比较,差异有统计意义(P<0.05)。结论高同型半胱氨酸血症对急性脑梗死患者预后产生不良影响,增加急性脑梗死患者复发率。
Objective To explore the influence of plasama homocysteine on acute cerebral infarction.Methods 150 cases with acute cerebral infarction was selected from December 2007 to December 2009,they were divided into observation group and control group according to raising of plasama homocysteine in 24 hours after being hospitalized.The neurologic impairment and activity of daily living were detected by the National Institutes of Health Stroke Scale（NIHSS）and BI index while being hospitalized and different time after onset;recurrence of cerebral infarction was recorded in one year.Results The scores of neurologic impairment and activity of daily in observation group after 4 and 24 weeks of onset compared with those in control group,there was statistical difference（P0.05）;the rate of recurrence of cerebral infarction in observation group compared with that in control group,there was statistical difference（P0.05）.Conclusions The high level of plasama homocysteine can produce harmful effects on acute cerebral infarction,and increase the rate of recurrence.
出处
《中国医药指南》
2011年第11期6-7,共2页
Guide of China Medicine
关键词
急性脑梗死
同型半胱氨酸
Acute cerebral infarction
Homocysteine
