摘要
目的探讨无创正压通气在慢性阻塞性肺病急性发作并Ⅱ型呼吸衰竭的应用。方法将50例重度COPD并Ⅱ型呼吸衰竭患者随机分为对照组和治疗组,对照组27例,治疗组23例。对照组用常规药物治疗,即给予抗生素、甲强龙、鼻导管吸氧等治疗;治疗组在常规治疗基础上加无创正压通气治疗。结果两组患者治疗前的基础情况和血气指标差异无统计学差异(P>0.05)。治疗后治疗组动脉血PH、氧分压(PaO2)、二氧化碳分压(PaCO2)明显改善(P<0.05),而对照组患者常规治疗后血气变化不明显。结论无创正压通气治疗AECOPD并Ⅱ型呼吸衰竭,可显著改善患者低氧血症,减少二氧化碳潴留。
Objective To study the clinical effect of non-invasive positive airway ventilation in the treament of severe COPD at acute exacerbation with type Ⅱ respiratory failure. Methods Fifty inpatients with sever AECOPD and type Ⅱ respiratory failure were divided into the treating group （n = 23 ） and the control group（ n = 27 ） randomly during January 2008 to August 2009. Patients in both two groups were treated with oxygen therapy, antibiotics, methyl prednisolone as routine treatment. The non-invasive positive airway ventilation was used in the treating group. Heart rate, respiratory frequency, and arterial blood gases were detected before and after 72 hours treat- ment. Results There were considerable improvements in the arterial blood gases in the treating group after treatment compared with the controls. Conclusion Non-invasivc positive pressure ventilation can be of great benefit to patients suffering from AECOPD and type Ⅱ respiratory failure.
出处
《临床肺科杂志》
2011年第5期691-692,共2页
Journal of Clinical Pulmonary Medicine
关键词
无创正压通气
慢性阻塞性肺病急性发作
呼吸衰竭
non-invasive positive pressure ventilation
acute exacerbation of chronic obstructive pulmonary disease
type Ⅱ respiratory failure
