摘要
目的:两种不同化疗方法治疗晚期胃肠肿瘤效果评价。方法:74例晚期胃肠肿瘤患者随机分为单一组和联合组,每组37例。单一组给予吡喃阿霉素静脉推注、HCPT静脉滴注、5-Fu静脉滴注及DDP静脉滴注,联合组予以吡喃阿霉素静脉推注、HCPT静脉滴注,5-Fu及DDP腹腔灌注;4个疗程后评价疗效,随诊1～2年。结果:联合组近期有效率为54.05%,不良反应轻,改善乏力、食欲减退方面明显;单一组近期有效率为43.24%,不良反应重(P<0.05)。结论:联合化疗法优势明显,适合临床应用。
Objective To value the therapeutic effect and toxicity of two route chemotherapy and intravenous chemotherapy in advanced gastric and colorectal cancer.Methods All the 74 patients suffering from advanced gastric and colorectal carcinoma were randomized into two groups,37 patients were treated by two route chemotherapy：intravenous chemotherapy with THP and HCPT,and intraperitoneal chemotherapy with 5-Fu and DDP.37 patients were treated by intravenous chemotherapy of THP.HCPT.5Fu and DDP.Each treatment period is 28 days.We have valued the therapeutic effect per two treatment periods at least for 1～2 years.Results The early rate of two route therapeutic effect was 54.05%,The reaction of toxicity was mild.The early rate of intravenous chemotherapeutic effect was 43.24%.The reaction of toxicity was serious（P0.05）.Conclusion Two route chemotherapy has more advantages than intra-venous chemotherapy with it＇s long survival time and mild toxicity.
出处
《吉林医学》
CAS
2011年第9期1683-1684,共2页
Jilin Medical Journal
关键词
晚期胃肠肿瘤
化疗
静脉滴注
Nadvanced gastric and colorectal carcinoma
Chemotherapy
Intravenous drip
