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肺错构瘤191例临床分析及文献复习 被引量:10

Clinical analysis of 191 pulmonary hamartoma cases with literature review
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摘要 目的总结肺错构瘤的临床特点、影像特征、诊断、治疗方法及预后。方法回顾性研究北京协和医院1983-2010年间病理确诊191例肺错构瘤的临床资料并结合文献复习讨论。结果 75.39%发生于40~70岁之间,平均50.86岁,男:女为1.247:1,63.87%无症状。均行CT,12.3%见爆米花样钙化,仅10.5%术前明确诊断。支气管镜切除2例;手术切除189例:其中胸腔镜肺楔形切除51例,肺局部切除59例,剜除54例,肺段或肺叶切除22例,左全肺切除1例,肺叶袖式切除2例。软骨型占90.8%,瘤体平均19.57mm。术后随访1~331个月均无继发肺癌及复发或恶变。结论肺错构瘤术前确诊率低,联合多种影像学手段有助于术前明确诊断并制定合理的手术方案,预后良好。 Objective To analyze the clinical features, image characteristics, diagnosis and treatment of pulmonary hamartoma(PH) as well as the prognosis. Methods Data of 191 cases with PH proved by pathologic examination during 1983 to 2010 in PUMCH was studied. Results PH occurred most frequently (75.39%) in patients aged 40 to 70 years, the mean age was 50.86 years, and the male to female ratio was 1.247∶1 in our series. 63.87% were symptomless. All patients underwent CT scan and the "popcorn" calcification was found in 12.3% of the cases. The preoperative diagnosis rate was 10.5%. Two cases underwent bronchoscopic resection. 189 cases underwent the following procedures:VATS wedge resection(51), local excision(59), enucleation(54), segmentectomy or lobectomy(22), pneumonectomy(1), sleeve resection(2). Chondroid hamartoma accounted for 90.8% of all cases. The mean transverse diameter was 19.57mm. No secondary lung cancer or recurrence or canceration was found during follow-ups from 1 to 331 months post-operatively. Conclusion The rate of preoperative diagnosis of PH is low. Combining multiple imagings may help to make a correct preoperative diagnosis and determination of appropriate surgical procedures. The prognosis of PH is satisfactory.
出处 《北京医学》 CAS 2011年第4期279-282,共4页 Beijing Medical Journal
关键词 肺错构瘤 间质瘤 影像特征 外科治疗 Pulmonary hamartoma Mesenchymoma Image characteristics Surgical treatment
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