摘要
目的研究核桃青皮的体外抑菌活性。方法选取金黄色葡萄球菌、大肠杆菌、枯草芽孢杆菌和深红酵母等重要指示菌为标靶,以最低抑菌浓度为指标,采用杯碟法对核桃青皮乙醇提取物的不同极性萃取部位进行抑菌活性的筛选。结果核桃青皮提取物对金黄色葡萄球菌和深红酵母不敏感,对大肠杆菌和枯草芽孢杆菌有显著的抑制作用;氯仿萃取部位对大肠杆菌和枯草芽孢杆菌有很好的抑制作用,最小抑菌浓度为62.5 mg·L-1,远低于其他极性部位。结论核桃青皮对大肠杆菌和枯草芽孢杆菌具有显著的抑菌活性。
OBJECTIVE To study the antimicrobial activity of different extracts from walnut peel（Juglans regia）.METHODS The antimicrobial activity of walnut peel was determined by agar diffusion method.The minimum inhibitory concentration（MIC） was used as the indexes aiming at the inhibition capacity of four kinds of indicator microorganisms（Staphyloccocus aureus,Escherichia coli,Bacillus subtilis,Rhodotorula rubra）.RESULTS The walnut peel exhibited a high sensitivity to E.coli and B.subtilis,but a low sensitivity to S.aureus and R.rubra in vitro.The extracts of chloroform exhibited the strongest inhibitory activity with a MIC of 62.5 mg·L-1.CONCLUSION The walnut peel has significant cytotoxicity against microorganism.
出处
《华西药学杂志》
CAS
CSCD
北大核心
2011年第2期150-152,共3页
West China Journal of Pharmaceutical Sciences
关键词
核桃青皮
萃取
抑菌活性
最小抑制浓度
Walnut peel（Juglans regia）
Extract
Antimicrobial activity
MIC
