老年缺血性脑梗死与颈动脉斑块危险因素分析被引量：3

Analysis of Carotid Atherosclerotic Plaque and Risk Factors of the Eldly Patients with Cerebral Infarction

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摘要目的:探讨老年人颈动脉粥样斑块及危险因素与缺血性脑梗死的关系。方法:将90例≥60岁的缺血性脑梗死老年患者作为观察组,60例同期非脑血管病患者作为对照组。进行颈动脉彩色多普勒检查,测量内中膜厚度(IMT),观察斑块形成情况。同时检测血压、血脂、血糖等项目。结果:颈动脉斑块发生率观察组为85.45%,对照组为65.46%,2组比较有显著性差异(P<0.05)。血压、血糖、血脂的升高是缺血性脑血管病颈动脉粥样斑块的危险因素。结论:颈动脉粥样硬化斑块形成是缺血性脑梗死的一个重要因素。年龄、高血压病、糖尿病、血脂异常与粥样硬化斑块形成有关。 Objective：To analyze the relationship between carotid atherosclerotic plaque and risk factors of the eldly patients with cerebral infarction. Methods：90 old patients with cerebral infarction were detected by color doppler and the levels of blood pressure,blood lipids,blood glucose,and compared with normal control group. Results：The incidence rate of carotid atherosclerotic plaque was 85.45% in the patients with cerebral infarction,it was 65.46% in normal control group（P〈0.05）.High blood pressure,high blood lipids were risk factors of carotid atherosclerotic plaque. Conclusion：Carotid atherosclerotic plaque is one of the important factors of cerebral infarction.High blood pressure,high blood lipids are associatied with the formation of carotid atherosclerotic plaque.

作者刘莉王汐赵雷陈晓敏

机构地区北京大学深圳医院

出处《现代临床医学》 2011年第2期105-106,共2页 Journal of Modern Clinical Medicine

关键词颈动脉粥样硬化斑块缺血性脑梗死危险因素 carotid atherosclerotic plaque cerebral infarction risk factor

分类号 R743 [医药卫生—神经病学与精神病学]

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参考文献4

1华扬何文段云友.等血管超声检查指南.中华超声影像学杂志,:30-32.
2Rosvall M, Janzon L, Berglund G,et al. Incident coronary events and case -fatality in relation to common carotid MT[J]. J Intem Meal,2005,257 (5) :430-437.
3黄延焱.代谢综合征颈动脉斑块相关因素分析[J].中国实用内科杂志,2008,28(8):648-651. 被引量：6
4季芳,刘汉利,李蕾,钟斐,张鹏翔,祁小娟.急性脑梗死与颈动脉及其下肢动脉粥样硬化斑块的关系[J].临床内科杂志,2007,24(7):453-454. 被引量：11

二级参考文献17

1王娟,周鸿,张振玲,史丽雅,张明智,陈望,杨兴洲.二维及彩色多普勒超声检查下肢动脉粥样硬化的价值[J].中国超声诊断杂志,2004,5(12):910-912. 被引量：9
2International Diabetes Federation. The IDF consensus worldwide definition of the metabolic syndrome[ EB/OL]. (2005 - 05 - 14) [2007- 10 - 15 ]. http://www. IDF. org/webdata/docs/IDF_ Meta_def_final.pdf.
3Hulthe J, Wikstrand J,Emanuelsson H, et al. Atherosclerotic changes in the carotid artery bulb as measured by B-mode ultrasound are associated with the extent of coronary atherosclerosis [ J ]. Stroke, 1997,28 (6) : 1189 - 1194.
4Hu G, Qiao Q, Tuomilehto J, et al. Prevalence of the metabolic syndrome and its relation to all-cause and cardiovascular mortality in nondiabetic European men and women [ J ]. Arch Intern Med, 2004,164(10) :1066 - 1076.
5Rosvall M, Janzon L, Berglund G, et al. Incident coronary events and case-fatality in relation to common carotid IMT [ J ]. J Intern Med ,2005,257 (5) :430 -437.
6Hollander M, Bots ML, Del Sol AI, et al. Carotid plaques increase the risk of stroke and subtypes of cerebral infarction in asymptomarie elderly: the Rotterdam Study [ J ]. Circulation, 2002, 105 (24) :2872 - 2877.
7Pearson TA, Mensah GA, Alexander RW, et al. Markers of inflammation and cardiovascular disease:application to clinical and public health practice: a statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association [ J ]. Circulation,2003,107 ( 3 ) :499 - 511.
8Meier-Ewert HK, Ridker PM, Rifai N, et al. Absence of diurinal variation of C-reactive protein concentrations in healthy human subjects[J]. Clin Chem ,2001,47(3 ) :426 -430.
9Rosvall M,Engstrom G,Janzon L,et al. The role of low grade inflammation as measured by C-reactive protein levels in the explanation of socioeconomic differences in carotid atherosclerosis [ J ]. Eur J Public Health,2007,17 (4) :340 - 347.
10Pasceri V, Willerson JT, Yeh ET. Direct proinflammatory effect of C-reactive protein on human endothelial cells [ J ]. Circulation, 2000,102(18) :2165 -2168.