摘要
本文介绍一家三姐妹的头颅平片在基底节区均可见对称性钙化。先证者女性,25岁时出现左侧肢体无力,病情渐进加重。神经系统检查发现智力轻度障碍,语言障碍,锥体束征及左半身感觉障碍。先证者的二位胞姐未见神经系统病征。全部病例从临床上可排除甲旁低(HPT),假性甲旁低(PHP),假假性甲旁低(PPHP)等疾病,故诊为家族性特发性基底节钙化症(FICBG)。本文材料提示,病人是否出现神经病征以及何时出现病征,脑组织受钙化病变累及的部位和程度起决定作用。用改善脑血循环的治疗可能减轻病征。
On the plain films of the skull taken from three sisters of one family,therewere bilateral symmetric calcification at the basal ganglia.The initial symptom of afemale proband was weakness on the left side of her body at her age of 25.Sincethen,the patient's condition was getting worse gradually with mild mental retarda-tion,speech disturbances;bilateral extensor plantar response and hemianesthesia onneurological examination.Two sisters of the proband showed no neurological abnor-malities.Practically in all three patients the diagnosis of HPT,PHP,PPHP could beruled out,Hence a familial idiopathic calcification of basal ganglia(FICBE)couldbe considered.It was suggested that whether and when neurological abnomalitiescould be present,entirely depended on the location and extent of the calcification inthe brain.It was possible to diminish the clinical symptoms by improving the circu-lation of the brain.
出处
《天津医药》
CAS
1990年第6期337-340,共4页
Tianjin Medical Journal
